Cheap Flights from San Diego to Missouri from $282 Return

Flight deals from San Diego to Missouri

Looking for cheap tickets from San Diego to Missouri, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

St Louis.$283 per passenger.Departing Sat, 14 Feb, returning Sat, 21 Feb.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from San Diego International on Sat, 14 Feb, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Sat, 21 Feb, arriving in San Diego International.Price includes taxes and charges.From $283, select.

Kansas City.$302 per passenger.Departing Thu, 19 Feb, returning Wed, 25 Feb.Return flight with Frontier Airlines and Spirit Airlines.Outbound indirect flight with Frontier Airlines, departs from San Diego International on Thu, 19 Feb, arriving in Kansas City International.Inbound indirect flight with Spirit Airlines, departs from Kansas City International on Wed, 25 Feb, arriving in San Diego International.Price includes taxes and charges.From $302, select.

Columbia.$476 per passenger.Departing Thu, 9 Apr, returning Mon, 13 Apr.Return flight with United.Outbound indirect flight with United, departs from San Diego International on Thu, 9 Apr, arriving in Columbia.Inbound indirect flight with United, departs from Columbia on Mon, 13 Apr, arriving in San Diego International.Price includes taxes and charges.From $476, select.

Springfield.$584 per passenger.Departing Tue, 3 Feb, returning Sat, 7 Feb.Return flight with Delta.Outbound indirect flight with Delta, departs from San Diego International on Tue, 3 Feb, arriving in Springfield-Branson Rg.Inbound indirect flight with Delta, departs from Springfield-Branson Rg on Sat, 7 Feb, arriving in San Diego International.Price includes taxes and charges.From $584, select.

See more deals

Flying from San Diego to Missouri

Arm yourself with these facts on the fly.

Cheapest flight found	$282
Cheapest month to fly	February
Average flight time	3 hrs, 22 mins
Cheapest airport to fly from	San Diego International
Most popular airline	Southwest Airlines

How to find cheap flights from San Diego to Missouri

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from San Diego to Missouri. Other savvy travellers recently found return flights from $282 and one-way tickets from $107 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from San Diego International into St Louis

At the moment, the lowest priced flight tickets to Missouri are from San Diego International Airport to St Louis Airport.

Fly in February

We crunched the flight calendar and found the cheapest time to fly from San Diego to Missouri is currently February.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from San Diego to anywhere you choose in Missouri.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from San Diego to Missouri go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Missouri to Missouri flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average San Diego to Missouri flight price?

We looked at all of the upcoming return flights from San Diego to Missouri we could find over the next 12 months. It looks like $282 is the best price. This is good, compared to the average Missouri ticket price of $411.

What is the cheapest month to fly from San Diego to Missouri?

The cheapest month to fly from San Diego to Columbia Airport is usually April. The cheapest month to fly from San Diego to Kansas City International Airport is usually February. The cheapest month to fly from San Diego to St Louis Airport is usually February. And the cheapest month to fly from San Diego to Springfield-Branson Rg Airport is usually February.

Which upcoming date is cheapest to fly from San Diego to Missouri on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from San Diego to Missouri on Saturday, 14 February 2026.

Are there any direct flights from San Diego to Missouri?

San Diego International Airport offers direct flights to Missouri.

If I'm flying from San Diego, where in Missouri is cheapest to fly into?

If you're flying from San Diego, the cheapest city in Missouri to fly into is St Louis. The cheapest airport serving St Louis at the moment is St Louis.