Cheap Flights from Des Moines to Sao Paulo

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Flight deals from Des Moines to Sao Paulo

Looking for a cheap last-minute deal or the best return flight from Des Moines to Sao Paulo? Find the lowest prices on one-way and return tickets right here.

Sao Paulo.$1,868 per passenger.Departing Wed, 10 Jun, returning Wed, 24 Jun.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Wed, 10 Jun, arriving in Sao Paulo Guarulhos.Inbound indirect flight with United, departs from Sao Paulo Guarulhos on Wed, 24 Jun, arriving in Des Moines.Price includes taxes and charges.From $1,868, select.

Sao Paulo.$1,973 per passenger.Departing Mon, 4 May, returning Mon, 25 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Mon, 4 May, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Delta, departs from Sao Paulo Guarulhos on Mon, 25 May, arriving in Des Moines.Price includes taxes and charges.From $1,973, select.

Sao Paulo.$2,124 per passenger.Departing Mon, 30 Mar, returning Mon, 6 Apr.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Mon, 30 Mar, arriving in Sao Paulo Guarulhos.Inbound indirect flight with United, departs from Sao Paulo Guarulhos on Mon, 6 Apr, arriving in Des Moines.Price includes taxes and charges.From $2,124, select.

Sao Paulo.$2,139 per passenger.Departing Wed, 1 Apr, returning Wed, 8 Apr.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Wed, 1 Apr, arriving in Sao Paulo Guarulhos.Inbound indirect flight with United, departs from Sao Paulo Guarulhos on Wed, 8 Apr, arriving in Des Moines.Price includes taxes and charges.From $2,139, select.

Sao Paulo.$2,330 per passenger.Departing Sat, 1 Aug, returning Sat, 8 Aug.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Sat, 1 Aug, arriving in Sao Paulo Guarulhos.Inbound indirect flight with United, departs from Sao Paulo Guarulhos on Sat, 8 Aug, arriving in Des Moines.Price includes taxes and charges.From $2,330, select.

Sao Paulo.$2,403 per passenger.Departing Thu, 12 Mar, returning Sun, 22 Mar.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Thu, 12 Mar, arriving in Sao Paulo Guarulhos.Inbound indirect flight with United, departs from Sao Paulo Guarulhos on Sun, 22 Mar, arriving in Des Moines.Price includes taxes and charges.From $2,403, select.

Sao Paulo.$2,444 per passenger.Departing Sat, 28 Feb, returning Sat, 14 Mar.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Des Moines on Sat, 28 Feb, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Sat, 14 Mar, arriving in Des Moines.Price includes taxes and charges.From $2,444, select.

Find the cheapest month to fly from Des Moines to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Sao Paulo flights are currently cheapest in June.

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Alternative Des Moines to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Des Moines to Sao Paulo? You could fly into the following airports instead.

Des Moines to Sao Paulo: Flight information

The things to know before you go.

Cheapest flight found	$1,868
Cheapest month to fly	June

Finding cheap flights from Des Moines to Sao Paulo: Frequently asked questions

How many airports are there in Sao Paulo?

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.

How much are return flights from Des Moines to Sao Paulo?

The best price we found for a return flight from Des Moines to Sao Paulo is $1,868. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Des Moines to Sao Paulo?

Currently, there are no airlines that fly direct from Des Moines to Sao Paulo. But we found flights with one or more stops from $1,868.

How many flights are there a week from Des Moines to Sao Paulo?

As of February 2026, there are no flights flying from Des Moines to Sao Paulo.

When is the cheapest time to fly from Des Moines to Sao Paulo?

The cheapest month to fly from Des Moines to Sao Paulo is usually June.

Which is the cheapest airport to fly into in Sao Paulo?

If you're flying from Des Moines Airport, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the centre of Sao Paulo. We've found flights into this airport from $1,868.

Which upcoming date is cheapest to fly from Des Moines Airport to Sao Paulo on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Sao Paulo on Wednesday, 10 June 2026.

Can I get a direct flight from Des Moines Airport to Sao Paulo?

No airlines currently offer direct flights between Des Moines Airport and Sao Paulo. Most routes have one or more stops.

How can I get the best flight deal from Des Moines Airport to Sao Paulo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Sao Paulo?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Sao Paulo?

In February, the average temperature is usually around 23°C. February is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is July, with temperatures averaging 12°C. The rainiest month is January.

Which is the cheapest airline to fly from Des Moines Airport to Sao Paulo with?

Currently, United offers the cheapest flight tickets to Sao Paulo.

Travelling from Des Moines International Airport (DSM) to Sao Paulo: what you need to know

The timezone in Sao Paulo is UTC-3. The city is two hours ahead of Des Moines, where Des Moines International Airport is located.
Give yourself plenty of time to get on your DSM to Sao Paulo flight. As a general rule, turn up two hours before international departures and an hour ahead for domestic flights.
Travelling during a peak time like a bank holiday? Expect longer queues at check-in and security. To give yourself peace of mind, arrive up to four hours before international flights and two hours ahead of domestic departures.
We make it a breeze to book flight tickets from DSM to Sao Paulo with a stopover. To see the options, uncheck 'Direct flights only.' Next, pick a flight that has a stop long enough to tour your chosen city. Some popular stopovers include:
- O'Hare International Airport (ORD)
- Dallas/Fort Worth International Airport (DFW)
- George Bush Intercontinental Airport (IAH)
Located around 6 kilometres from the centre of Des Moines, DSM can be reached in about 15 minutes by car. Travelling on public transport takes roughly 45 minutes.
Searching for a hotel near DSM? If you're catching an early flight from Des Moines International Airport to Sao Paulo, these stays will put you moments from check-in:
80.45% of flights leaving Des Moines International Airport arrive at their destination according to schedule. Given its reliable on-time performance, you're unlikely to be delayed when taking off from DSM.
You'll find DSM at 5800 Fleur Drive, Suite 201.

How to find the cheapest flights from Des Moines International Airport (DSM) to Sao Paulo

$1,088 is the cheapest price we've found for a one-way Des Moines International Airport to Sao Paulo flight. A round-trip ticket right now is $1,868. Depending on when you want to go and the availability, these fares can change.
Booking ahead of time is often the key to finding a cheap flight from DSM to Sao Paulo. Fares tend to rise as demand increases, so the closer you get to departure, the more it could cost you.
If you're willing to be flexible with your trip dates, take advantage of the 'Whole month' search tool. It'll find the cheapest price across every month when searching for your Des Moines International Airport to Sao Paulo ticket.
Snapping up a cheap flight from DSM to Sao Paulo is easy with Price Alerts. All you need to do is create one of these automatic notifications and we'll notify you as soon as a cheaper option becomes available.
Find an affordable flight from Des Moines International Airport to Sao Paulo with the help of our filters. Select your preferred times, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Sao Paulo

Sao Paulo-Guarulhos International Airport (GRU)

Sao Paulo-Guarulhos International Airport (GRU) is around 26 kilometres from the centre of Sao Paulo. If you're opting for a ride-share or a cab, the drive will take roughly 30 minutes.
It typically takes 1 hour 20 minutes to get there by public transport.
If you're arriving on a late flight from Des Moines International Airport to Sao Paulo, nothing beats the convenience of staying near the terminal. Grab your luggage from the carousel and then be showered and resting soon after at one of these accommodation options near GRU:
Grab a Sao Paulo-Guarulhos International Airport rental car and explore Sao Paulo and beyond with your own set of wheels. Foco, Localiza and Movida are popular providers to choose from here.
Get the best deal by reserving your vehicle from Sao Paulo-Guarulhos International Airport about two weeks ahead of your flight from DSM to Sao Paulo.

Sao Paulo/Congonhas Airport (CGH)

Sao Paulo/Congonhas Airport (CGH) is roughly 10 kilometres from central Sao Paulo. Following your flight from Des Moines International Airport to Sao Paulo, it'll take you around 15 minutes to reach the heart of the city in a cab or ride-share.
The trip will take roughly 35 minutes on public transport.
Hang the 'Do not disturb' sign on your door and unwind at a hotel near CGH. Here are a few options where you can take a load off after your DSM to Sao Paulo flight:
Forget about inconvenient public transport schedules or long cab lines. Grab a Sao Paulo/Congonhas Airport rental car and let the journey unfold your way. Compare availability and rates from Foco, Localiza and Movida.
Snap up the best price by securing your ride from CGH three weeks in advance. You can also expect to have a greater range of vehicles.

Viracopos Airport (VCP)

Viracopos Airport (VCP) is around 97 kilometres from central Sao Paulo. It takes about 1 hour 15 minutes to get to the city centre in a ride-share or cab after your flight from Des Moines International Airport to Sao Paulo.
The journey takes roughly 3 hours 25 minutes when travelling by public transport.
Enjoy a quiet, low-key start to your trip by checking in to a hotel near VCP after your DSM to Sao Paulo flight. Recover from your travel day or simply give yourself time to get your bearings in a new destination at:
Whether you'd like a zippy mini for solo travel or a spacious SUV to fit the family, you'll find the perfect Viracopos Airport rental car for you. Browse the types of wheels available from providers such as Foco, Localiza and Movida.
Enjoy a payoff when you plan ahead. Book your ride from VCP four weeks before your flight from Des Moines International Airport to Sao Paulo for the best deals.

Best time to go to Sao Paulo

Carefully consider your travel dates before securing your flight from Des Moines International Airport to Sao Paulo. The city buzzes in high season, but prices are usually higher and major attractions can get busy. Plan your trip to Sao Paulo in the low season if you want a more relaxed vibe.
The warmest month in Sao Paulo is February, with temperatures ranging between 18ºC and 28ºC. Book your Des Moines International Airport to Sao Paulo flight ticket then if you enjoy this type of weather.
If you want to travel in cooler conditions, look for a cheap ticket from DSM to Sao Paulo in July when temperatures average between 12ºC and 25ºC.

More about Sao Paulo

When it comes to looking for somewhere to lay your head, you'll find the most popular stays in Sao Paulo right here. Explore these options after you've booked your flight from Des Moines International Airport to Sao Paulo:
Ibirapuera Park and Sao Paulo Museum of Art are just the start of the top attractions to add to your Sao Paulo itinerary. Keep the momentum going by heading to Avenida Paulista.

Explore more of Brazil

You've visited Sao Paulo, now it's time to explore other corners of Brazil. Journey about 499 kilometres north-east to Belo Horizonte to check off its must-visit sights. From Abilio Barreto Historical Museum to Matiz Arte Objeto and Deck Vertedouro, you'll have a packed itinerary ahead.
If you want to check out another great destination in Brazil, head for Curitiba, about 338 kilometres south-west of Sao Paulo. Jardim Botanico de Curitiba, Museu Oscar Niemeyer and Largo da Ordem are highlights.