Cheap Flights from Portland to St Louis

Compare Portland to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Find the cheapest month to fly from Portland to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Portland to St Louis flights are currently cheapest in February.

Portland to St Louis: Alternative routes

Compare routes from Portland to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Portland to St Louis: Flight information

The things to know before you go.
Cheapest flight found$563
Cheapest month to flyFebruary

Finding cheap flights from Portland to St Louis: Frequently asked questions

The best price we found for a return flight from Portland to St Louis is $563. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Portland to St Louis. But we found flights with one or more stops from $563.
As of February 2026, there are no flights flying from Portland to St Louis.
The cheapest month to fly from Portland to St Louis is usually February.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Portland Airport to St Louis Airport on Thursday, 19 February 2026.
No airlines currently offer direct flights between Portland Airport and St Louis Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to St Louis.

Flying from Portland International Jetport Airport (PWM) to Lambert-St. Louis International Airport (STL): what you need to know

  • The timezone in St Louis is UTC-5, which is one hour behind Portland.

  • Leave plenty of time to make your PWM to STL flight. As a rule of thumb, arrive two hours before international departures and an hour ahead for domestic flights.

  • Travelling during a peak time such as August? Public holidays and other popular periods can lead to longer lines and delays at check-in and security. Play things extra safe and arrive up to four hours before an international flight and two hours before a domestic departure.

  • If you want to explore another city along the way, simply uncheck 'Direct flights only' when searching for your ticket from Portland International Jetport Airport to Lambert-St. Louis International Airport. These are the most popular stopovers between PWM and STL:

    • Ronald Reagan National Airport

    • Detroit Metropolitan Wayne County Airport

    • Baltimore/Wash International Thurgood Marshall Airport

How to find the cheapest flights from Portland International Jetport Airport (PWM) to Lambert-St. Louis International Airport (STL)

  • At the moment, $405 is the cheapest price we've seen for a one-way Portland International Jetport Airport to Lambert-St. Louis International Airport flight. The best price for a return ticket is $563. Bear in mind that fares can change due to availability when booking.

  • To pick up cheap tickets from PWM to STL, book ahead. Airlines usually offer lower prices when flights are first made available.

  • The 'Whole month' search function shows you the cheapest flights from Portland International Jetport Airport to Lambert-St. Louis International Airport across every month. It's a good way to find a bargain if your trip dates aren't set in stone.

  • You won't have to check back in every day to find out if fares have dropped when you create a Price Alert. We'll update you the moment the price changes on cheap flights from PWM to STL.

  • Discover the right flight for you with the help of the filters. To see the 'Fastest,' 'Best' or 'Cheapest' flights from Portland International Jetport Airport to Lambert-St. Louis International Airport, use the 'Sort by' function. You can also filter results by departure and arrival times, airline, and journey duration.

Handy information about Portland International Jetport Airport (PWM)

  • PWM is located at 1001 Westbrook Street.

  • 82.15% of flights leaving Portland International Jetport Airport touch down at their destination on schedule. Given its dependable on-time performance, you're unlikely to experience delays when flying out of PWM.

  • Central Portland to Portland International Jetport Airport is around 8 kilometres. Depending on traffic, it'll take you about 15 minutes to get there if you're driving, ride-sharing or catching a cab.

  • Planning to catch public transport? Expect a trip time of around 40 minutes.

  • Searching for a convenient hotel near PWM? If you're catching an early flight from Portland International Jetport Airport to Lambert-St. Louis International Airport, these stays will put you moments from your departure lounge:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • STL is located at 10701 Lambert International Blvd..

  • Lambert-St. Louis International Airport is roughly 26 kilometres from central St Louis. The drive time takes around 20 minutes.

  • When travelling by public transport, expect a journey time of about 35 minutes.

When to fly to Lambert-St. Louis International Airport (STL)

  • The quietest month for a flight from Portland International Jetport Airport to Lambert-St. Louis International Airport is April, while July is the busiest. Pick the best time to visit St Louis based on whether you prefer a more relaxed vibe or a faster pace.

  • Lock in your flight from Portland International Jetport Airport to Lambert-St. Louis International Airport for July if you'd like to explore St Louis during its warmest month. You can expect temperatures of between 17ºC and 33ºC.

  • Search for cheap tickets from PWM to STL in January if you'd rather travel during cooler conditions. Temperatures are at their lowest around then, ranging between -8ºC and 7ºC on average.

Explore more of United States

  • You've done St Louis, now it's time to explore more of United States. Travel about 418 kilometres north-east to Chicago to tick off its must-visit sights. From Millennium Park to Art Institute of Chicago and LandShark Beer Garden at Navy Pier, you've got a jam-packed schedule ahead.

  • Indianapolis is another well-known destination in United States and is around 370 kilometres east of St Louis. No journey is complete without visiting The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.