Cheap Flights from Louisville Muhammad Ali International to Santo Domingo

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Flight deals from Louisville Muhammad Ali International to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Louisville Muhammad Ali International to Santo Domingo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Louisville Muhammad Ali International to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Louisville Muhammad Ali International to Santo Domingo flights are currently cheapest in March.

Alternative Louisville Muhammad Ali International to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Louisville Muhammad Ali International to Santo Domingo? You could fly into the following airports instead.

Louisville to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found$593
Cheapest month to flyMarch

Finding cheap flights from Louisville Muhammad Ali International to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Louisville Muhammad Ali International to Santo Domingo is $593. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Louisville Muhammad Ali International to Santo Domingo. But we found flights with one or more stops from $593.
As of February 2026, there are no flights flying from Louisville Muhammad Ali International to Santo Domingo.
The cheapest month to fly from Louisville Muhammad Ali International to Santo Domingo is usually March.
If you're flying from Louisville Muhammad Ali International Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from $593.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Louisville Muhammad Ali International Airport to Santo Domingo on Monday, 23 March 2026.
No airlines currently offer direct flights between Louisville Muhammad Ali International Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In February, the average temperature is usually around 25°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Allegiant Air offers the cheapest flight tickets to Santo Domingo.

Flying from Louisville International Airport-Standiford Field (SDF) to Santo Domingo: what you need to know

  • Santo Domingo's timezone is UTC-4, which is the same as Louisville (the location of Louisville International Airport-Standiford Field).

  • For a stress-free journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. That way, you can comfortably board your SDF to Santo Domingo flight.

  • Taking off during a peak period like school or public holidays? Expect longer lines at check-in and security. To play it safe, arrive up to four hours before international flights and two hours before domestic departures.

  • We make it easy to book flight tickets from SDF to Santo Domingo with a stopover. To see all the options, uncheck 'Direct flights only.' Then, select a flight with a stop long enough to explore the city of your choice. Some popular stopovers include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Newark Liberty International Airport (EWR)

    • Miami International Airport (MIA)

  • SDF is about 14 kilometres from central Louisville. If you're catching a cab, driving or ride-sharing from the centre, it'll take you 25 minutes or so to get there, depending on traffic. If you're planning to take public transport, expect the journey time to be around 2 hours 40 minutes.

  • Have an early flight from Louisville International Airport-Standiford Field to Santo Domingo? Avoid the last-minute rush to the terminal (and enjoy a little extra shut-eye) by choosing one of these stays close to SDF:

  • 77.69% of flights leaving from Louisville International Airport-Standiford Field touch down at their destination on schedule.

  • The address for SDF is 600 Terminal Drive.

How to find the cheapest flights from Louisville International Airport-Standiford Field (SDF) to Santo Domingo

  • $266 is currently the lowest price for a one-way Louisville International Airport-Standiford Field to Santo Domingo flight. Return flight tickets start at $593. These fares can change depending on availability and demand.

  • Don't wait until the last moment. You're more likely to land cheap flights from SDF to Santo Domingo if you book in advance. Airlines often offer some fantastic early bird rates.

  • If you're flexible with your travel dates, try using the 'Whole month' tool. It'll show you the lowest price across every month when looking for a Louisville International Airport-Standiford Field to Santo Domingo ticket.

  • Snapping up a cheap flight from SDF to Santo Domingo is easy with Price Alerts. Simply set up one of these automatic notifications and we'll get in touch when a deal gets even better.

  • Tailor your trip with filters. Choose your preferred departure and arrival times, total journey duration and airlines. You can also sort results by 'Best,' 'Fastest' or 'Cheapest' flights from Louisville International Airport-Standiford Field to Santo Domingo.

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • The distance from Las Americas International Airport (SDQ) to central Santo Domingo is roughly 32 kilometres. It takes around 30 minutes to reach the centre driving.

  • If you're coming in on a late flight from Louisville International Airport-Standiford Field to Santo Domingo, few things beat the convenience of staying close to the terminal. Grab your bags from the carousel and then be showered and resting soon after at one of these accommodation options near SDQ:

  • Explore without limits with a Las Americas International Airport rental car. Book your wheels from Final Rentals, FlexWays or INFINITY RENT and discover more of Santo Domingo and beyond.

  • Booking your vehicle from Las Americas International Airport around one week in advance of your flight from SDF to Santo Domingo can help you lock in the best possible rate.

Dr. Joaquin Balaguer International Airport (JBQ)

  • Dr. Joaquin Balaguer International Airport (JBQ) is around 19 kilometres from central Santo Domingo. Once you've disembarked your flight from Louisville International Airport-Standiford Field to Santo Domingo, it'll take you around 25 minutes to reach the heart of the city in a ride-share or cab.

  • Unpack and relax not long after your SDF to Santo Domingo flight at Micro Hotel Condo Suites. This comfortable accommodation option is a quick drive from JBQ.

  • Pick up a Dr. Joaquin Balaguer International Airport rental car and experience more with your own wheels. FlexWays is just moments from arrivals, so you can hit the road without delay.

  • Get your ideal vehicle, not just whatever's left, by reserving your ride from JBQ before your arrival. You can also avoid paying more than you have to, especially during busy airport times.

Best time to go to Santo Domingo

  • Before scheduling your flights from Louisville International Airport-Standiford Field to Santo Domingo, consider which time of year works best for you. High season in Santo Domingo offers a lively atmosphere and plenty of things to do, while the off-season brings cheaper deals on hotels and smaller crowds.

  • Before booking a Louisville International Airport-Standiford Field to Santo Domingo flight ticket, think about the kind of weather forecast you're hoping for. September is the warmest month in Santo Domingo, with temperatures ranging from 23ºC to 33ºC.

  • Search for cheap tickets from SDF to Santo Domingo in February if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between 19ºC and 29ºC on average.

More about Santo Domingo

  • Start your Santo Domingo trip right by choosing the ideal place to stay. After booking your flight from Louisville International Airport-Standiford Field to Santo Domingo, browse our range of accommodation options including:

  • There are so many things to see and do in this city it can be tricky to work out where to begin. National Palace, Alcazar de Colon and Basilica Cathedral of Santa Maria la Menor are top sights which should be on any well-planned Santo Domingo itinerary.

Explore more of Dominican Republic

  • You've done Santo Domingo, now it's time to discover other parts of Dominican Republic. Travel about 105 kilometres east to La Romana to check off its leading sights. From Dye Fore Golf Course of Casa de Campo to Minitas Beach and La Estrella Park, your itinerary will be busy.

  • Around 161 kilometres north-west of Santo Domingo, Puerto Plata is another favourite stop in Dominican Republic. Experience this destination's highlights firsthand at Fortaleza San Felipe, Teleferico Puerto Plata Cable Car and Malecon Puerto Plata.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.