Cheap Flights from Des Moines to Raleigh / Durham from $466

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Flight deals from Des Moines to Raleigh / Durham

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to Raleigh / Durham Airport? If you want to travel next month, return fares start from $466. Find the lowest prices on one-way and return tickets right here.

Durham.$466 per passenger.Departing Tue, 4 Aug, returning Tue, 11 Aug.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Des Moines on Tue, 4 Aug, arriving in Raleigh / Durham.Inbound indirect flight with Southwest Airlines, departs from Raleigh / Durham on Tue, 11 Aug, arriving in Des Moines.Price includes taxes and charges.From $466, select.

Durham.$467 per passenger.Departing Fri, 4 Sep, returning Sun, 6 Sep.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Des Moines on Fri, 4 Sep, arriving in Raleigh / Durham.Inbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Sun, 6 Sep, arriving in Des Moines.Price includes taxes and charges.From $467, select.

Durham.$547 per passenger.Departing Tue, 8 Dec, returning Tue, 29 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Tue, 8 Dec, arriving in Raleigh / Durham.Inbound indirect flight with Delta, departs from Raleigh / Durham on Tue, 29 Dec, arriving in Des Moines.Price includes taxes and charges.From $547, select.

Durham.$548 per passenger.Departing Tue, 8 Dec, returning Sat, 2 Jan.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Tue, 8 Dec, arriving in Raleigh / Durham.Inbound indirect flight with United, departs from Raleigh / Durham on Sat, 2 Jan, arriving in Des Moines.Price includes taxes and charges.From $548, select.

Durham.$568 per passenger.Departing Fri, 24 Jul, returning Sun, 26 Jul.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Des Moines on Fri, 24 Jul, arriving in Raleigh / Durham.Inbound indirect flight with Frontier Airlines, departs from Raleigh / Durham on Sun, 26 Jul, arriving in Des Moines.Price includes taxes and charges.From $568, select.

Durham.$684 per passenger.Departing Wed, 11 Nov, returning Sun, 15 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Wed, 11 Nov, arriving in Raleigh / Durham.Inbound indirect flight with Delta, departs from Raleigh / Durham on Sun, 15 Nov, arriving in Des Moines.Price includes taxes and charges.From $684, select.

Find the cheapest month to fly from Des Moines to Raleigh / Durham

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Raleigh / Durham flights are currently cheapest in August.

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Des Moines to Raleigh / Durham: Alternative routes

Compare routes from Des Moines to Durham below. You may find an airport to fly into that's cheaper, faster, or easier than Raleigh / Durham.

Raleigh / Durham

17km from central Durham

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from $466

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Des Moines to Durham: Flight information

The things to know before you go.

Cheapest flight found	$466
Cheapest month to fly	August

Finding cheap flights from Des Moines to Raleigh / Durham: Frequently asked questions

How much are return flights from Des Moines to Raleigh / Durham?

The best price we found for a return flight from Des Moines to Raleigh / Durham is $466. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Des Moines to Raleigh / Durham?

Currently, there are no airlines that fly direct from Des Moines to Raleigh / Durham. But we found flights with one or more stops from $466.

How many flights are there a week from Des Moines to Raleigh / Durham?

As of July 2026, there are no flights flying from Des Moines to Raleigh / Durham.

When is the cheapest time to fly from Des Moines to Raleigh / Durham?

The cheapest month to fly from Des Moines to Raleigh / Durham is usually August.

Which upcoming date is cheapest to fly from Des Moines Airport to Raleigh / Durham Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Raleigh / Durham Airport on Tuesday, 4 August 2026.

Can I get a direct flight from Des Moines Airport to Raleigh / Durham Airport?

No airlines currently offer direct flights between Des Moines Airport and Raleigh / Durham Airport. Most routes have one or more stops.

How can I find the best flight deal to Raleigh / Durham?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Raleigh / Durham but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Durham?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Durham is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Des Moines Airport to Raleigh / Durham with?

Currently, Southwest Airlines offers the cheapest flight tickets to Raleigh / Durham.

Flying from Des Moines Airport (DSM) to Raleigh / Durham Airport (RDU): what you need to know

The timezone in Durham is UTC-5, which is one hour ahead of Des Moines.
Arriving two hours before an international flight and one hour ahead of a domestic departure are tried-and-true travel tips. Make sure you're at the airport on time to catch your DSM to RDU flight.
During popular months like August, it's best to get to the airport well in advance. Arrive two hours before domestic departures and four hours ahead for an international flight whenever you're flying during peak periods in general.
If you want to explore another city along the way, just uncheck 'Direct flights only' when searching for your ticket from Des Moines Airport to Raleigh / Durham Airport. These are the top stopovers between DSM and RDU:
- Chicago O'Hare International Airport
- Atlanta Hartsfield-Jackson Airport
- St Louis Airport

How to find the cheapest flights from Des Moines Airport (DSM) to Raleigh / Durham Airport (RDU)

$193 is the best price for a one-way Des Moines Airport to Raleigh / Durham Airport flight. Return flights start at $466. These prices may change depending on demand.
It's usually best to book early if you're looking for cheap tickets from DSM to RDU. That's because flight prices are based on demand, which tends to rise closer to departure.
If you're willing to be flexible with your travel plans, use the 'Whole month' search tool. It'll find the cheapest price in every month when looking for a flight from Des Moines Airport to Raleigh / Durham Airport.
You won't have to check every day to see if fares have gone down when you set up a Price Alert. We'll notify you as soon as the price changes on cheap flights from DSM to RDU.
Select your ideal departure and arrival times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to find the best deals on flights from Des Moines Airport to Raleigh / Durham Airport.

Handy information about Des Moines Airport (DSM)

The address for DSM is 5800 Fleur Drive, Suite 201.
77% of flights that take off from Des Moines Airport touch down at their destination on time.
To get to Des Moines Airport from central Des Moines, it takes around 15 minutes if you're going by car. Of course, this depends on traffic conditions. It's approximately 11 kilometres from the airport to the city centre.
Catching public transport? Expect a journey time of around 30 minutes.
Get your journey off to a stress-free start by staying near DSM. Whether you're taking an early flight from Des Moines Airport to Raleigh / Durham Airport or just don't want to be rushed, these stays are ideal:

Arriving at Raleigh / Durham Airport (RDU)

The last thing you want is a lengthy trip to your hotel if you're getting in late on a Des Moines Airport to Raleigh / Durham Airport flight. Book one of these accommodation options near RDU instead:
Travel at your own speed with a Raleigh / Durham Airport rental car. Book your wheels from Thrifty, Dollar or Hertz and see more of Durham and beyond.
To lock in the lowest price, reserve your ride from Raleigh / Durham Airport around one week before your trip.

When to fly to Raleigh / Durham Airport (RDU)

The quietest month for a flight from Des Moines Airport to Raleigh / Durham Airport is March, while July is the busiest. Choose the best time to go to Durham based on whether you prefer a more relaxed vibe or a faster pace.
The warmest month in Durham is July, with the temperature ranging between 19ºC and 33ºC. Lock in your flights from Des Moines Airport to Raleigh / Durham Airport in this month if this is the kind of weather you like.
January sees average temperatures of between -3ºC and 13ºC. Search for cheap tickets from DSM to RDU around that time if you want to travel when it's cooler.

Explore more of the United States

Charlotte is just one of the many cities in the United States waiting to be discovered after you've experienced Durham. Around 193 kilometres away to the south-west, check out popular attractions including Bechtler Museum of Modern Art, Discovery Place and NASCAR Hall of Fame.
Around 418 kilometres north-east of Durham, Baltimore is another favourite stop in the United States. Experience major highlights starting with National Aquarium, Baltimore Aquarium and Washington Monument and Mount Vernon Place.