Cheap Flights from Des Moines to Syracuse

Compare Des Moines to Syracuse flight deals

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Flight deals from Des Moines to Syracuse

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to Syracuse Airport? If you want to travel next month, return fares start from $609. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Des Moines to Syracuse

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Syracuse flights are currently cheapest in July.

Des Moines to Syracuse: Alternative routes

Compare routes from Des Moines to Syracuse below. You may find an airport to fly into that's cheaper, faster, or easier than Syracuse.

Des Moines to Syracuse: Flight information

The things to know before you go.
Cheapest flight found$609
Cheapest month to flyJuly

Finding cheap flights from Des Moines to Syracuse: Frequently asked questions

The best price we found for a return flight from Des Moines to Syracuse is $609. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Des Moines to Syracuse. But we found flights with one or more stops from $609.
As of June 2026, there are no flights flying from Des Moines to Syracuse.
The cheapest month to fly from Des Moines to Syracuse is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Syracuse Airport on Friday, 10 July 2026.
No airlines currently offer direct flights between Des Moines Airport and Syracuse Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Syracuse but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Syracuse is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Delta offers the cheapest flight tickets to Syracuse.

Flying from Des Moines Airport (DSM) to Syracuse Airport (SYR): what you need to know

  • To ensure you catch your DSM to SYR flight, allow plenty of time for things like baggage drop and finding your gate. Turning up two hours before international departures and one hour before domestic flights is the standard rule.

  • Travelling during a peak month like August? Public holidays and other high seasons can lead to longer lines and delays at check-in and security. Be extra cautious and arrive up to four hours ahead of international flights and two hours before a domestic departure.

  • We make it a piece of cake to book a flight with a stopover. To see your options for tickets from Des Moines Airport to Syracuse Airport, uncheck 'Direct flights only.' Then, choose a flight with a stop long enough to tour your chosen city. Worthwhile stopovers between DSM and SYR include:

    • Chicago O'Hare International Airport

    • Detroit Wayne County Airport

    • Minneapolis St Paul Airport

How to find the cheapest flights from Des Moines Airport (DSM) to Syracuse Airport (SYR)

  • $538 is currently the lowest price for a one-way Des Moines Airport to Syracuse Airport flight. Return flights start from $609. These fares can change based on availability and demand.

  • To find cheap tickets from DSM to SYR, book ahead. Airlines tend to offer lower fares when flights are first made available.

  • Finding cheap flights from Des Moines Airport to Syracuse Airport is easy if you're flexible with your dates. Use the 'Whole month' search tool to see the best prices across the month and land a great deal.

  • Landing cheap flights from DSM to SYR is a breeze with Price Alerts. All you need to do is create one of these automatic alerts and we'll notify you when a lower fare pops up.

  • Lock in the ideal flight for you by using the filters. To see the 'Fastest,' 'Cheapest' or 'Best' flights from Des Moines Airport to Syracuse Airport, use the 'Sort by' tool. You can also filter results by arrival and departure times, airline, and journey duration.

Handy information about Des Moines Airport (DSM)

  • DSM is located at 5800 Fleur Drive, Suite 201.

  • Of all flights leaving Des Moines Airport, 77% land on time at their destination.

  • Des Moines Airport is about 11 kilometres from central Des Moines. If you're catching a taxi, ride-sharing or driving from the centre, it'll take you 15 minutes or so to get there, depending on the traffic.

  • Planning to take public transport? Expect a journey time of around 30 minutes.

  • Booked an early flight from Des Moines Airport to Syracuse Airport? Avoid the hassle of rushing to the airport (and sneak in some extra snooze time) by choosing one of these hotels near DSM:

Arriving at Syracuse Airport (SYR)

Getting from Syracuse Airport (SYR) to central Syracuse

  • SYR is located at City Hall.

  • Syracuse Airport to the centre of Syracuse has a drive time of about 20 minutes. It's approximately 11 kilometres away.

  • If you're taking public transport, expect a journey time of about 35 minutes.

When to fly to Syracuse Airport (SYR)

  • It's time to work out your dates for your flight from Des Moines Airport to Syracuse Airport. August is the busiest month to visit Syracuse. If you prefer a more low-key vibe, go in January.

  • The warmest month in Syracuse is July, with temperatures ranging between 14ºC and 28ºC. Lock in your flights from Des Moines Airport to Syracuse Airport in this month if this is the kind of weather you like.

  • January has average temperatures of between -12ºC and 3ºC. Look for cheap tickets from DSM to SYR sometime then if you want to travel when it's cooler.

Explore more of the United States

  • You've seen Syracuse, now it's time to explore other parts of the United States. Travel around 322 kilometres south-east to New York to tick off its top sights. From Central Park to Statue of Liberty and Metropolitan Museum of Art, there's plenty to keep you busy.

  • Philadelphia is another essential stop in the United States and is around 354 kilometres south of Syracuse. No trip is complete without seeing Independence Hall, Liberty Bell and Philadelphia Museum of Art.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.