Cheap Flights from Detroit Wayne County to Santiago

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Travellers and bags, 1 Adult, Economy

Compare Detroit Wayne County to Santiago flight deals

Find the cheapest month or even day of the year to fly to Santiago

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Flight deals Cheapest month Find the best route Route info FAQs Tips and advice

Flight deals from Detroit Wayne County to Santiago

Looking for a cheap last-minute deal or the best return flight from Detroit Wayne County Airport to Santiago Airport? If you want to travel next month, return fares start from $1,403. Find the lowest prices on one-way and return tickets right here.

Santiago.$1,245 per passenger.Departing Wed, 17 Feb, returning Sat, 27 Feb.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Wed, 17 Feb, arriving in Santiago.Inbound indirect flight with Delta, departs from Santiago on Sat, 27 Feb, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,245, select.

Santiago.$1,404 per passenger.Departing Tue, 1 Sep, returning Mon, 28 Sep.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Tue, 1 Sep, arriving in Santiago.Inbound indirect flight with United, departs from Santiago on Mon, 28 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,404, select.

Santiago.$1,421 per passenger.Departing Wed, 30 Sep, returning Sun, 11 Oct.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Wed, 30 Sep, arriving in Santiago.Inbound indirect flight with United, departs from Santiago on Sun, 11 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,421, select.

Santiago.$1,522 per passenger.Departing Thu, 1 Oct, returning Sun, 4 Oct.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 1 Oct, arriving in Santiago.Inbound indirect flight with United, departs from Santiago on Sun, 4 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,522, select.

Santiago.$1,715 per passenger.Departing Wed, 16 Dec, returning Wed, 13 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Wed, 16 Dec, arriving in Santiago.Inbound indirect flight with Delta, departs from Santiago on Wed, 13 Jan, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,715, select.

Santiago.$2,127 per passenger.Departing Sun, 6 Dec, returning Sun, 20 Dec.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Sun, 6 Dec, arriving in Santiago.Inbound indirect flight with United, departs from Santiago on Sun, 20 Dec, arriving in Detroit Wayne County.Price includes taxes and charges.From $2,127, select.

Santiago.$2,475 per passenger.Departing Thu, 27 Aug, returning Sun, 30 Aug.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 27 Aug, arriving in Santiago.Inbound indirect flight with United, departs from Santiago on Sun, 30 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From $2,475, select.

Santiago.$2,494 per passenger.Departing Sat, 28 Nov, returning Sun, 29 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Sat, 28 Nov, arriving in Santiago.Inbound indirect flight with Delta, departs from Santiago on Sun, 29 Nov, arriving in Detroit Wayne County.Price includes taxes and charges.From $2,494, select.

Find the cheapest month to fly from Detroit Wayne County to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Detroit Wayne County to Santiago flights are currently cheapest in February.

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Detroit Wayne County to Santiago: Alternative routes

Compare routes from Detroit Wayne County to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Santiago

2km from central Santiago

ClosestCheapest

from $1,244

Search flights

Puerto Plata

36km from central Santiago

from $1,462

Search flights

Detroit to Santiago: Flight information

The things to know before you go.

Cheapest flight found	$1,245
Cheapest month to fly	February

Finding cheap flights from Detroit Wayne County to Santiago: Frequently asked questions

How much are return flights from Detroit Wayne County to Santiago?

The best price we found for a return flight from Detroit Wayne County to Santiago is $1,244. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Detroit Wayne County to Santiago?

Currently, there are no airlines that fly direct from Detroit Wayne County to Santiago. But we found flights with one or more stops from $1,245.

How many flights are there a week from Detroit Wayne County to Santiago?

As of August 2026, there are no flights flying from Detroit Wayne County to Santiago.

When is the cheapest time to fly from Detroit Wayne County to Santiago?

The cheapest month to fly from Detroit Wayne County to Santiago is usually February.

Which upcoming date is cheapest to fly from Detroit Wayne County Airport to Santiago Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Detroit Wayne County Airport to Santiago Airport on Wednesday, 17 February 2027.

Can I get a direct flight from Detroit Wayne County Airport to Santiago Airport?

No airlines currently offer direct flights between Detroit Wayne County Airport and Santiago Airport. Most routes have one or more stops.

How can I find the best flight deal to Santiago?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Santiago?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Detroit Wayne County Airport to Santiago with?

Currently, Delta offers the cheapest flight tickets to Santiago.

Flying from Detroit Wayne County Airport (DTW) to Santiago Airport (STI): what you need to know

Santiago is one hour ahead of Detroit and is in the UTC-4 timezone.
For a stress-free journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This ensures you have enough time to catch your DTW to STI flight.
You can expect longer queues in popular months such as July. Arriving up to four hours ahead of an international flight and two hours for domestic departures will help ensure a smooth travel experience.
We make it easy to book a flight with a stopover. To see your options for tickets from Detroit Wayne County Airport to Santiago Airport, uncheck 'Direct flights only.' Then, choose a flight with a stop long enough to tour your chosen city. Top stopovers between DTW and STI include:
- New York Newark Airport
- Miami International Airport
- San Juan Luis Munoz Marin Airport

How to find the cheapest flights from Detroit Wayne County Airport (DTW) to Santiago Airport (STI)

$661 is currently the best price for a one-way Detroit Wayne County Airport to Santiago Airport flight. Return flights start at $1,244. These prices may change based on demand.
It's often best to book ahead of time if you're looking for cheap tickets from DTW to STI. That's because flight prices are based on demand, which tends to increase closer to the date of departure.
The 'Whole month' search function shows you the cheapest flights from Detroit Wayne County Airport to Santiago Airport throughout the month. It's a good way to snap up a bargain if your trip dates aren't set in stone.
Never miss a deal on cheap flights from DTW to STI by setting up a Price Alert. We'll send you an email or notification on the app when a special offer becomes available.
Pick your ideal departure and arrival times, airlines and number of stops with the filters. Alternatively, sort your results by 'Cheapest' to get the best deals on flights from Detroit Wayne County Airport to Santiago Airport.

Handy information about Detroit Wayne County Airport (DTW)

You'll find DTW at 1 Detroit Metro Airport.
74% of flights that leave from Detroit Wayne County Airport reach their destination on time.
To reach Detroit Wayne County Airport from central Detroit, it'll take about 30 minutes if you're planning to drive. This depends on traffic, however. It's approximately 32 kilometres from the airport to the city centre.
Expect a journey time of about 1 hour when using public transport.
Need a handy hotel close to DTW? If you're catching an early flight from Detroit Wayne County Airport to Santiago Airport, these accommodation options will have you sleeping moments from your check-in counter:

Arriving at Santiago Airport (STI)

If you're arriving on a late Detroit Wayne County Airport to Santiago Airport flight, few things beat the convenience of being close to the terminal. Grab your bags from the carousel and then be showered and relaxing not long after at one of these accommodation options near STI:
Grab a Santiago Airport rental car and discover Santiago and beyond with your own set of wheels. America, Zezgo Rent a Car and Alamo are top outlets to choose from here.
For the lowest price, reserve your vehicle from Santiago Airport about one week before you set off.

Getting from Santiago Airport (STI) to central Santiago

Santiago Airport is roughly 16 kilometres from central Santiago. The drive time takes about 25 minutes.
It typically takes 40 minutes if you're travelling by public transport.

When to fly to Santiago Airport (STI)

August is the busiest month for flights from Detroit Wayne County Airport to Santiago Airport. To skip the crowds, visit Santiago in October.
Book your flight from Detroit Wayne County Airport to Santiago Airport for August if you'd like to visit Santiago during its warmest month. You can expect temperatures of between 21ºC and 33ºC.
January sees average temperatures of between 16ºC and 29ºC. Search for cheap tickets from DTW to STI around that time if you like travelling in cooler conditions.

Explore more of the Dominican Republic

You've done Santiago, now it's time to explore other parts of the Dominican Republic. Journey about 137 kilometres south-east to Santo Domingo to tick off its popular sights. From Catedral Primada de las Americas to Alcazar de Colon and The Cathedral of the Americas, you'll have a packed itinerary ahead.
If you're ready to explore another major destination in the Dominican Republic, head for Santo Domingo Este, about 145 kilometres south-east of Santiago. Lago los tres ojos, National Aquarium and La Cueva del Eden are among the biggest draws.