Cheap Flights from Minneapolis St Paul to Panama City

Compare Minneapolis St Paul to Panama City flight deals

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Flight deals from Minneapolis St Paul to Panama City

Looking for a cheap last-minute deal or the best return flight from Minneapolis St Paul to Panama City? Find the lowest prices on one-way and return tickets right here.

Panama City.$1,055 per passenger.Departing Tue, 11 Aug, returning Tue, 18 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Minneapolis St Paul on Tue, 11 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Tue, 18 Aug, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,055, select.

Panama City.$1,090 per passenger.Departing Fri, 8 May, returning Tue, 19 May.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Fri, 8 May, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 19 May, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,090, select.

Panama City.$1,122 per passenger.Departing Sat, 12 Sep, returning Sat, 19 Sep.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Sat, 12 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sat, 19 Sep, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,122, select.

Panama City.$1,168 per passenger.Departing Wed, 17 Jun, returning Wed, 24 Jun.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Wed, 17 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Wed, 24 Jun, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,168, select.

Panama City.$1,171 per passenger.Departing Sat, 18 Apr, returning Tue, 28 Apr.Return flight with Copa.Outbound indirect flight with Copa, departs from Minneapolis St Paul on Sat, 18 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Tue, 28 Apr, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,171, select.

Panama City.$1,243 per passenger.Departing Tue, 24 Mar, returning Tue, 31 Mar.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Tue, 24 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 31 Mar, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,243, select.

Panama City.$1,383 per passenger.Departing Wed, 8 Jul, returning Fri, 24 Jul.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Wed, 8 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 24 Jul, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,383, select.

Panama City.$1,401 per passenger.Departing Thu, 26 Feb, returning Mon, 9 Mar.Return flight with United.Outbound indirect flight with United, departs from Minneapolis St Paul on Thu, 26 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Mon, 9 Mar, arriving in Minneapolis St Paul.Price includes taxes and charges.From $1,401, select.

Find the cheapest month to fly from Minneapolis St Paul to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Minneapolis St Paul to Panama City flights are currently cheapest in August.

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Alternative Minneapolis St Paul to Panama City routes

Looking for the cheapest, fastest or easiest route from Minneapolis St Paul to Panama City? You could fly into the following airports instead.

Minneapolis to Panama City: Flight information

The things to know before you go.

Cheapest flight found	$1,055
Cheapest month to fly	August

Finding cheap flights from Minneapolis St Paul to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Minneapolis St Paul to Panama City?

The best price we found for a return flight from Minneapolis St Paul to Panama City is $1,055. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Minneapolis St Paul to Panama City?

Currently, there are no airlines that fly direct from Minneapolis St Paul to Panama City. But we found flights with one or more stops from $1,055.

How many flights are there a week from Minneapolis St Paul to Panama City?

As of February 2026, there are no flights flying from Minneapolis St Paul to Panama City.

When is the cheapest time to fly from Minneapolis St Paul to Panama City?

The cheapest month to fly from Minneapolis St Paul to Panama City is usually August.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Minneapolis St Paul Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $1,055.

Which upcoming date is cheapest to fly from Minneapolis St Paul Airport to Panama City on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Minneapolis St Paul Airport to Panama City on Tuesday, 11 August 2026.

Can I get a direct flight from Minneapolis St Paul Airport to Panama City?

No airlines currently offer direct flights between Minneapolis St Paul Airport and Panama City. Most routes have one or more stops.

How can I get the best flight deal from Minneapolis St Paul Airport to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In February, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Minneapolis St Paul Airport to Panama City with?

Currently, Delta offers the cheapest flight tickets to Panama City.

Flying from Minneapolis-St. Paul International Airport (MSP) to Panama City: what you need to know

Minneapolis (the location of Minneapolis-St. Paul International Airport) and Panama City follow the same timezone — UTC-5.
For hassle-free travel, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This ensures you have enough time to catch your MSP to Panama City flight.
Delays at check-in and security are more likely if you're travelling during high season, so give yourself a little extra breathing room. A good general rule for peak times? Get there up to four hours ahead for international flights and two hours for domestic departures.
Consider adding a stopover to potentially save on your flight ticket from MSP to Panama City. All you need to do is uncheck 'Direct flights only' during your search. Give yourself a breather (and maybe even a better deal) by stopping at one of these popular airports:
- Miami International Airport (MIA)
- Orlando International Airport (MCO)
- Cancun International Airport (CUN)
Travelling from central Minneapolis to MSP takes around 25 minutes by public transport. If you ride-share, drive or take a cab, you'll cover the 11 kilometres in 20 minutes or so, depending on traffic.
In search of a hotel near MSP? If you're catching an early flight from Minneapolis-St. Paul International Airport to Panama City, these accommodation options will get you from your pillow to the plane in no time:
When it comes to the on-time performance of Minneapolis-St. Paul International Airport, 77.37% of flights arrive within the scheduled time frame.
The address for MSP is 6040 28th Avenue South.

How to find the cheapest flights from Minneapolis-St. Paul International Airport (MSP) to Panama City

$575 is currently the lowest price for a one-way Minneapolis-St. Paul International Airport to Panama City flight. A return flight ticket starts from $1,055. These prices may change based on demand and availability.
Don't leave things to the last moment. You're more likely to pick up cheap flights from MSP to Panama City if you book early. Airlines often have some great early bird discounts.
Scoring cheap tickets from Minneapolis-St. Paul International Airport to Panama City is easier if you're flexible with your travel dates. Try using the 'Whole month' search tool to get the lowest prices across the month and score a fantastic deal.
Spend less time searching for cheap flights from MSP to Panama City by creating a Price Alert. You'll get an email or push notification on the app when a new low fare is offered.
Find a cheap flight from Minneapolis-St. Paul International Airport to Panama City with the help of our filters. Select your ideal duration, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

Tocumen International Airport (PTY) to central Panama City takes around 20 minutes by car. The centre is roughly 21 kilometres away.
Getting to the centre on public transport takes around 1 hour 5 minutes.
The last thing you need is a long journey to your hotel if you're getting in late on a flight from Minneapolis-St. Paul International Airport to Panama City. Stay at one of these accommodation options near PTY instead:
Pick up a Tocumen International Airport rental car and explore Panama City and beyond with your own set of wheels. Avis, Dollar and MEX are leading providers you can book with here.
Lock in the best deal by reserving your vehicle from Tocumen International Airport about three weeks ahead of your flight from MSP to Panama City.

Marcos A. Gelabert International Airport (PAC)

Central Panama City is about 2 kilometres from Marcos A. Gelabert International Airport (PAC). After your flight from Minneapolis-St. Paul International Airport to Panama City has hit the runway and you've navigated your way to arrivals, expect a drive of about 5 minutes.
You can expect the trip to take roughly 25 minutes on public transport.
You'll find some great places ready to welcome you near PAC. Settle in and get cosy after your MSP to Panama City flight at any of these well-located options:
The fastest way to reach your destination is with a Marcos A. Gelabert International Airport rental car. Pick up a set of wheels from Thrifty, Avis or Alamo and set off in the blink of an eye.
Lock in the lowest price by reserving your ride from PAC three weeks ahead of time. You'll also have access to a greater selection of vehicles.

Panama Pacifico Airport (BLB)

Panama Pacifico Airport (BLB) is about 16 kilometres from central Panama City. It takes about 20 minutes to get to the city centre by car once you've hopped off your flight from Minneapolis-St. Paul International Airport to Panama City.
If you don't want to make the journey to the centre, find a hotel near BLB. Settle in at one of these stays after your MSP to Panama City flight:
Be in control of the next leg of your journey by picking up a Panama Pacifico Airport rental car. Sixt, Dollar and Thrifty make getting on the road effortless.
About one week ahead of your flight from Minneapolis-St. Paul International Airport to Panama City is a good time to secure your ride from BLB. You're likely to snag a better deal or pick up some early bird promotions.

Best time to go to Panama City

Carefully consider your dates before booking your flight from Minneapolis-St. Paul International Airport to Panama City. The city buzzes in high season, but hotel rates are typically higher and top attractions can get crowded. Plan your trip to Panama City in low season if you prefer a quieter vibe.
The warmest month in Panama City is March, with temperatures ranging between 21ºC and 32ºC. Book your Minneapolis-St. Paul International Airport to Panama City flight ticket then if you enjoy this type of weather.
If you want cooler conditions, look for a cheap ticket from MSP to Panama City in February when temperatures average between 22ºC and 31ºC.

More about Panama City

Start your Panama City trip off on the right foot by choosing the perfect place to stay. As soon as you've booked your flight from Minneapolis-St. Paul International Airport to Panama City, browse our selection of hotels including:
There are so many things to see and do in this city it can be tricky to know where to start. Casco Viejo, Panama Canal Museum and Cinta Costera are leading attractions which should feature on any well-planned Panama City itinerary.

Explore more of Panama

Panama City has plenty to offer, but there are so many other corners of Panama you should also see. Around 322 kilometres west of Panama City, a visit to David will keep your itinerary packed. Start with attractions like Parque Cervantes, Altos del Rio Park and Coquito Hills Park.
Santiago de Veraguas is another sought-after destination in Panama and is around 193 kilometres south-west of Panama City. No journey is complete without visiting Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.