Cheap Flights from San Diego to Palermo from $1,287

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Flight deals from San Diego to Palermo

Looking for a cheap last-minute deal or the best return flight from San Diego to Palermo Airport? If you want to travel next month, return fares start from $1,632. Find the lowest prices on one-way and return tickets right here.

Palermo.$1,287 per passenger.Departing Tue, 11 Aug, returning Thu, 20 Aug.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Tue, 11 Aug, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Thu, 20 Aug, arriving in San Diego International.Price includes taxes and charges.From $1,287, select.

Palermo.$1,411 per passenger.Departing Mon, 7 Sep, returning Wed, 16 Sep.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Mon, 7 Sep, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Wed, 16 Sep, arriving in San Diego International.Price includes taxes and charges.From $1,411, select.

Palermo.$1,494 per passenger.Departing Sun, 30 Aug, returning Thu, 17 Sep.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Sun, 30 Aug, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Thu, 17 Sep, arriving in San Diego International.Price includes taxes and charges.From $1,494, select.

Palermo.$1,503 per passenger.Departing Thu, 1 Apr, returning Wed, 7 Apr.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Thu, 1 Apr, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Wed, 7 Apr, arriving in San Diego International.Price includes taxes and charges.From $1,503, select.

Palermo.$1,526 per passenger.Departing Wed, 30 Sep, returning Wed, 7 Oct.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Wed, 30 Sep, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Wed, 7 Oct, arriving in San Diego International.Price includes taxes and charges.From $1,526, select.

Palermo.$1,587 per passenger.Departing Thu, 1 Oct, returning Thu, 8 Oct.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Thu, 1 Oct, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Thu, 8 Oct, arriving in San Diego International.Price includes taxes and charges.From $1,587, select.

Palermo.$1,632 per passenger.Departing Thu, 9 Jul, returning Wed, 22 Jul.Return flight with Lufthansa.Outbound indirect flight with Lufthansa, departs from San Diego International on Thu, 9 Jul, arriving in Palermo.Inbound indirect flight with Lufthansa, departs from Palermo on Wed, 22 Jul, arriving in San Diego International.Price includes taxes and charges.From $1,632, select.

Palermo.$2,658 per passenger.Departing Thu, 18 Jun, returning Mon, 6 Jul.Return flight with British Airways.Outbound indirect flight with British Airways, departs from San Diego International on Thu, 18 Jun, arriving in Palermo.Inbound indirect flight with British Airways, departs from Palermo on Mon, 6 Jul, arriving in San Diego International.Price includes taxes and charges.From $2,658, select.

Palermo.$2,799 per passenger.Departing Sat, 6 Jun, returning Sat, 13 Jun.Return flight with Delta.Outbound indirect flight with Delta, departs from San Diego International on Sat, 6 Jun, arriving in Palermo.Inbound indirect flight with Delta, departs from Palermo on Sat, 13 Jun, arriving in San Diego International.Price includes taxes and charges.From $2,799, select.

Palermo.$2,850 per passenger.Departing Sun, 19 Jul, returning Sun, 9 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from San Diego International on Sun, 19 Jul, arriving in Palermo.Inbound indirect flight with Delta, departs from Palermo on Sun, 9 Aug, arriving in San Diego International.Price includes taxes and charges.From $2,850, select.

Palermo.$5,738 per passenger.Departing Tue, 23 Jun, returning Sat, 19 Sep.Return flight with British Airways.Outbound indirect flight with British Airways, departs from San Diego International on Tue, 23 Jun, arriving in Palermo.Inbound indirect flight with British Airways, departs from Palermo on Sat, 19 Sep, arriving in San Diego International.Price includes taxes and charges.From $5,738, select.

Find the cheapest month to fly from San Diego to Palermo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Diego to Palermo flights are currently cheapest in August.

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San Diego to Palermo: Alternative routes

Compare routes from San Diego to Palermo below. You may find an airport to fly into that's cheaper, faster, or easier than Palermo.

Palermo

24km from central Palermo

ClosestCheapest

from $1,287

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Trapani Birgi

80km from central Palermo

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San Diego to Palermo: Flight information

The things to know before you go.

Cheapest flight found	$1,276
Cheapest month to fly	August

Finding cheap flights from San Diego to Palermo: Frequently asked questions

How much are return flights from San Diego to Palermo?

The best price we found for a return flight from San Diego to Palermo is $1,287. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from San Diego to Palermo?

Currently, there are no airlines that fly direct from San Diego to Palermo. But we found flights with one stop from $1,287.

How many flights are there a week from San Diego to Palermo?

As of June 2026, there are no flights flying from San Diego to Palermo.

When is the cheapest time to fly from San Diego to Palermo?

The cheapest month to fly from San Diego to Palermo is usually August.

Which upcoming date is cheapest to fly from San Diego to Palermo Airport on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from San Diego to Palermo Airport on Tuesday, 11 August 2026.

Can I get a direct flight from San Diego to Palermo Airport?

No airlines currently offer direct flights between San Diego and Palermo Airport. Most routes have one or more stops.

How can I find the best flight deal to Palermo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Palermo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Palermo?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Palermo is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from San Diego to Palermo with?

The cheapest airline that flies to Palermo is Lufthansa .

Travelling from San Diego to Palermo Falcone Borsellino Airport (PMO): What you need to know

Palermo is nine hours ahead of San Diego. Palermo Falcone Borsellino Airport is located in Palermo, which is in the UTC+1 timezone.
Your flight from San Diego to PMO won't wait if you're running late, so don't forget to check in on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're travelling internationally.
July is a busy month for travelling. If you're taking off then or during a major holiday like July Fourth, get there even earlier. Aim for at least two hours ahead for domestic flights and up to four hours for international journeys.

Airports in San Diego

San Diego International Airport (SAN)

Stopovers are a great opportunity to explore a new city or just have a break during your trip. When looking for a cheap flight from San Diego to PMO, deselect 'Direct flights only' to explore all potential stops. London Heathrow Airport (LHR) is an option when leaving from San Diego International Airport (SAN).
The journey from central San Diego to SAN takes about 25 minutes by public transport. If you drive, ride-share or get a taxi, you'll cover the 5 kilometres in 15 minutes or so, depending on traffic.
Catching an early flight from San Diego to Palermo Falcone Borsellino Airport? Avoid the mad dash to the terminal (and get some extra shut-eye) by choosing one of these stays near San Diego International Airport:
When it comes to San Diego International Airport's on-time performance, 74% of flights arrive within the scheduled time frame.
You'll find SAN at N Harbour Dr.

McClellan-Palomar Airport (CLD)

The distance from San Diego's city centre to CLD is about 48 kilometres. Consider the available transport options and potential delays when planning the quickest way to get to the airport.
Start your holiday early with an additional night away from home. Before catching your San Diego to PMO flight, kick back in one of these hotels close to McClellan-Palomar Airport:
Flights from McClellan-Palomar Airport have a proven record for punctuality, with 88% of them touching down as planned.

About Palermo Falcone Borsellino Airport (PMO)

Consider booking a hotel close to PMO if you have a late flight from San Diego to Palermo Falcone Borsellino Airport. Pick one of these accommodation options and call it a night faster:
Get the best deal by reserving your vehicle around four weeks ahead of your San Diego to Palermo Falcone Borsellino Airport flight.

Getting from Palermo Falcone Borsellino Airport (PMO) to central Palermo

Palermo Falcone Borsellino Airport is around 32 kilometres from the centre of Palermo. It takes around 40 minutes or so to drive to the city.
Travelling on public transport typically takes 50 minutes.

How to find the cheapest flights from San Diego to Palermo Falcone Borsellino Airport (PMO)

Currently, $644 is the lowest price we've found for a one-way ticket from San Diego to Palermo Falcone Borsellino Airport. The cheapest price for a return flight is $1,287. Remember fares may change due to availability at the time of booking.
Booking in advance is often the key to scoring a cheap flight from San Diego to PMO. Fares tend to rise as seats fill up, so the closer your departure date, the more you'll likely pay.
Affordable San Diego to Palermo Falcone Borsellino Airport tickets are easier to find when your travel dates are flexible. Use the 'Whole month' tool to compare fares across every month and then fly out on the cheapest day.
Never miss a deal on plane tickets from San Diego to PMO by creating a Price Alert. We'll send you an email or push notification on the app when fares go down.
Tailor your flights using filters. Pick your ideal departure and arrival times, airlines and total journey duration. You can also sort your results by 'Best,' 'Cheapest' or 'Fastest' flights from San Diego to Palermo Falcone Borsellino Airport.

The best time to fly from San Diego to Palermo Falcone Borsellino Airport (PMO)

It's time to work out when to book your flight from San Diego to Palermo Falcone Borsellino Airport (PMO). July is when most people visit Palermo. If a slower pace sounds more appealing, think about going in December.
Lock in a San Diego to PMO plane ticket departing in July if you want to experience the city during its warmest month. You can expect temperatures in Palermo to range from 21ºC to 34ºC.
February has temperatures of between 6ºC and 16ºC. Search for cheap tickets from San Diego to Palermo Falcone Borsellino Airport around that time if you want to travel in cooler conditions.

More about Palermo

When it comes to searching for somewhere to lay your head, you'll find the top stays in Palermo right here. Check out these options after you've booked your flight from San Diego to Palermo Falcone Borsellino Airport:
Every great journey has to include a little sightseeing. Golfo di Mondello, Piazza Pretoria and Duomo di Palermo are must-do's during your Palermo adventure.

Explore more of Italy

You've done Palermo, now it's time to discover other parts of Italy. Travel around 193 kilometres southeast to Catania to check off its leading sights. From Roman Amphitheatre of Catania to Piazza del Duomo and La Pescheria, you'll have a packed itinerary ahead.
Around 209 kilometres east of Palermo, Messina is another favourite stop in Italy. Start your sightseeing at Duomo di Messina, Cathedral of Messina (Duomo) and Astronomical Clock of the Cathedral of Messina.