Cheap Flights from Panama City to Cali

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Compare Panama City to Cali flight deals

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Flight deals from Panama City to Cali

Looking for a cheap last-minute deal or the best return flight from Panama City to Cali Airport? If you want to travel next month, return fares start from $479. Find the lowest prices on one-way and return tickets right here.

Cali.$473 per passenger.Departing Fri, 23 Oct, returning Tue, 3 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 23 Oct, arriving in Cali.Inbound direct flight with Copa departs from Cali on Tue, 3 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $473, select.

Cali.$479 per passenger.Departing Tue, 6 Oct, returning Sun, 11 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 6 Oct, arriving in Cali.Inbound direct flight with Copa departs from Cali on Sun, 11 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$479 per passenger.Departing Fri, 24 Jul, returning Mon, 3 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 24 Jul, arriving in Cali.Inbound direct flight with Copa departs from Cali on Mon, 3 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$479 per passenger.Departing Fri, 28 Aug, returning Tue, 15 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 28 Aug, arriving in Cali.Inbound direct flight with Copa departs from Cali on Tue, 15 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$479 per passenger.Departing Thu, 10 Sep, returning Tue, 15 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Thu, 10 Sep, arriving in Cali.Inbound direct flight with Copa departs from Cali on Tue, 15 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$479 per passenger.Departing Sun, 9 Aug, returning Fri, 14 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 9 Aug, arriving in Cali.Inbound direct flight with Copa departs from Cali on Fri, 14 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$479 per passenger.Departing Thu, 16 Jul, returning Sun, 19 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Thu, 16 Jul, arriving in Cali.Inbound direct flight with Copa departs from Cali on Sun, 19 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $479, select.

Cali.$483 per passenger.Departing Tue, 3 Nov, returning Sun, 8 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 3 Nov, arriving in Cali.Inbound indirect flight with Avianca, departs from Cali on Sun, 8 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $483, select.

Cali.$493 per passenger.Departing Fri, 11 Dec, returning Mon, 14 Dec.Return flight with Wingo.Outbound direct flight with Wingo departs from Balboa on Fri, 11 Dec, arriving in Cali.Inbound direct flight with Wingo departs from Cali on Mon, 14 Dec, arriving in Balboa.Price includes taxes and charges.From $493, select.

Cali.$546 per passenger.Departing Sat, 24 Apr, returning Sat, 1 May.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sat, 24 Apr, arriving in Cali.Inbound direct flight with Copa departs from Cali on Sat, 1 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $546, select.

Cali.$546 per passenger.Departing Tue, 22 Sep, returning Thu, 29 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 22 Sep, arriving in Cali.Inbound direct flight with Copa departs from Cali on Thu, 29 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $546, select.

Cali.$546 per passenger.Departing Wed, 25 Nov, returning Wed, 2 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 25 Nov, arriving in Cali.Inbound direct flight with Copa departs from Cali on Wed, 2 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $546, select.

Cali.$559 per passenger.Departing Fri, 15 Jan, returning Thu, 4 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 15 Jan, arriving in Cali.Inbound indirect flight with Avianca, departs from Cali on Thu, 4 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $559, select.

Cali.$561 per passenger.Departing Thu, 3 Jun, returning Mon, 7 Jun.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 3 Jun, arriving in Cali.Inbound indirect flight with Avianca, departs from Cali on Mon, 7 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $561, select.

Cali.$632 per passenger.Departing Tue, 3 Nov, returning Sun, 8 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 3 Nov, arriving in Cali.Inbound direct flight with Copa departs from Cali on Sun, 8 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $632, select.

Cali.$640 per passenger.Departing Wed, 30 Dec, returning Fri, 15 Jan.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 30 Dec, arriving in Cali.Inbound indirect flight with Avianca, departs from Cali on Fri, 15 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $640, select.

Find the cheapest month to fly from Panama City to Cali

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Cali flights are currently cheapest in July.

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Direct flights from Panama City to Cali

Panama City to Cali: Alternative routes

Compare routes from Panama City to Cali below. You may find an airport to fly into that's cheaper, faster, or easier than Cali.

Cali

23km from central Cali

ClosestCheapest

from $473

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Buenaventura

64km from central Cali

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Panama City to Cali: Flight information

The things to know before you go.

Cheapest flight found	$473
Cheapest month to fly	October
Average flight time	1 hr, 36 mins
Most popular airline	Copa
Average flights per week	88

Finding cheap flights from Panama City to Cali: Frequently asked questions

How much are return flights from Panama City to Cali?

The best price we found for a return flight from Panama City to Cali is $473. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Panama City to Cali?

1 hour and 35 minutes is the average flight time from Panama City to Cali.

Which airlines fly direct from Panama City to Cali?

Copa, United and KLM fly direct from Panama City to Cali.

How many flights are there a week from Panama City to Cali?

As of July 2026, there are 88 flights per week flying from Panama City to Cali.

When is the cheapest time to fly from Panama City to Cali?

The cheapest month to fly from Panama City to Cali is usually October.

Which upcoming date is cheapest to fly from Panama City to Cali Airport on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Cali Airport on Friday, 23 October 2026.

Can I get a direct flight from Panama City to Cali Airport?

Yes – the average flight time is 1 hour and 35 minutes.

How can I find the best flight deal to Cali?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Cali but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Cali?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Cali is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Panama City to Cali with?

The cheapest airline that flies to Cali is Copa .

Travelling from Panama City to Alfonso Bonilla Aragon International Airport (CLO): What you need to know

Start your holiday planning by working out where you'll board your flight from Panama City to Alfonso Bonilla Aragon International Airport (CLO). Panama City Tocumen International Airport (PTY) and Panama Pacifico International Airport (BLB) are the two main airports in Panama City.
Around 1 hour 40 minutes is the usual time it takes for a direct Panama City to Alfonso Bonilla Aragon International Airport flight.
Cali (where Alfonso Bonilla Aragon International Airport is located) and Panama City share the UTC-5 timezone. Easily coordinate travel plans without worrying about time differences.
With 28 direct flights a week between the two airports, Panama City Tocumen International Airport (PTY) to Alfonso Bonilla Aragon International Airport (CLO) is the busiest route. Copa Airlines operates the earliest flight at 9:12am. If you prefer to make the most of your day before you fly, the last departure from PTY to CLO is with Copa Airlines at 9:46pm.
For hassle-free travel, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This will give you plenty of time to catch your flight from Panama City to CLO.
Head to the airport even earlier during popular months like January. Aim for two hours before a domestic departure and as much as four hours for international flights. After checking in, you can use any extra time to relax or go over your itinerary.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

You can take a direct flight from Panama City to Alfonso Bonilla Aragon International Airport (CLO) departing from Panama City Tocumen International Airport (PTY).
When departing from PTY, you can take a direct flight from Panama City to Alfonso Bonilla Aragon International Airport with Copa Airlines.
The majority of passengers prefer to fly with Copa from PTY to CLO.
Copa takes the top spot for on-time performance. A reliable 91.84% of its departures on this route reach their destination on schedule.
Travelling from central Panama City to PTY takes around 50 minutes by public transport. If you ride-share, drive or grab a taxi, you'll cover the 24 kilometres in 35 minutes or so, depending on traffic.
Want a leisurely start to your break? Stay near Panama City Tocumen International Airport. Whether you have an early flight from Panama City to Alfonso Bonilla Aragon International Airport or prefer not to rush, these hotels are the ideal choice:
Panama City Tocumen International Airport has a strong on-time performance, so you're less likely to experience disruptions. Departures from PTY land on schedule 88% of the time.

Panama Pacifico International Airport (BLB)

Consider starting your trip from Panama Pacifico International Airport (BLB). You can book a direct Panama City to Alfonso Bonilla Aragon International Airport (CLO) plane ticket with departures from here.
From BLB, direct flights from Panama City to CLO can be booked with Wingo.
On the BLB to CLO route, Copa Airlines Colombia is the preferred choice for many passengers.
Book with Copa Airlines Colombia if being on time is your priority. Its flights between Panama Pacifico International Airport and Alfonso Bonilla Aragon International Airport land as scheduled 90.91% of the time.
BLB is about 6 kilometres from central Panama City. It'll take you 10 minutes or so to get to the airport by car from the city centre. Public transport takes approximately 20 minutes.
Want to enjoy an extra night away before catching your Panama City to CLO flight? Relax in a hotel near Panama Pacifico International Airport before your break officially begins. Here's where you can stay:
The majority of flights that depart Panama Pacifico International Airport touch down at their destination right on cue. It maintains a strong on-time performance rate of 88%.

About Alfonso Bonilla Aragon International Airport (CLO)

Have a late flight from Panama City to Alfonso Bonilla Aragon International Airport? Don't let it end in exhaustion. Check in to one of these hotels near CLO and be in snooze mode sooner:
Get the best deal by booking your vehicle around two weeks ahead of your Panama City to Alfonso Bonilla Aragon International Airport flight.

Getting from Alfonso Bonilla Aragon International Airport (CLO) to central Cali

Alfonso Bonilla Aragon International Airport is around 21 kilometres from the centre of Cali. It takes around 30 minutes or so to drive to the city.
Travelling by public transport typically takes 50 minutes.

How to find the cheapest flights from Panama City to Alfonso Bonilla Aragon International Airport (CLO)

The cheapest price we've found for a one-way ticket from Panama City to Alfonso Bonilla Aragon International Airport is $140. For a return flight on this route, the best price is $473. Depending on the availability when you book, these fares can change.
Book 11 months before you want to travel. Pricing trends show that this is the ideal window for finding cheap flights from Panama City to CLO.
Organise your trip for April. That's the best month for scoring a great bargain on Panama City to Alfonso Bonilla Aragon International Airport tickets. If you're flexible with your dates, use the 'Whole month' tool to find the cheapest price across every month.
You don't need to check back in every day to find out if fares have dropped when you create a Price Alert. We'll let you know the moment a lower fare pops up on plane tickets from Panama City to CLO.
Filters make it easier to find a bargain for your flight from Panama City to Alfonso Bonilla Aragon International Airport. Pick the airlines, flight times and stops that check all your boxes. Then sort the results by 'Cheapest' to find the best price quickly.

The best time to fly from Panama City to Alfonso Bonilla Aragon International Airport (CLO)

Picture the kind of break you want when deciding the best time to fly. December is the quietest month to go to Cali. July is when most people book flights from Panama City to Alfonso Bonilla Aragon International Airport (CLO), which may be perfect if you enjoy travelling when it's busier.
The warmest month in Cali is September, with temperatures ranging between 15ºC and 29ºC. Book your Panama City to CLO plane ticket then if you enjoy this type of weather.
Search for cheap tickets from Panama City to Alfonso Bonilla Aragon International Airport in January if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between 14ºC and 27ºC.

More about Cali

When it comes to searching for somewhere to lay your head, you'll find the most popular stays in Cali right here. Explore these hotels after you've booked your flight from Panama City to Alfonso Bonilla Aragon International Airport:
Cristo Rey and El Retiro Park are just a couple of the top attractions to add to your Cali itinerary. Continue your sightseeing adventures at Parque Simón Bolívar.

Explore more of Colombia

Pereira is just one of the many places in Colombia waiting to be discovered once you've seen the sights of Cali. Around 161 kilometres away to the northeast, its best attractions include Paisaje Cultural Cafetero, Reserva Natural, Termales de San Vicente and Lugar De Contemplación Monte Tabor.
If you're looking to explore another major destination in Colombia, head for Ibague, about 161 kilometres northeast of Cali. Alexander von Humboldt Botanical Garden, Libertador Park and Museo de Arte del Tolima are highlights.