Cheap Flights from Panama City to Italy from $1,402

Looking for a cheap last-minute deal or the best return flight from Panama City to Italy? If you want to travel next month, return fares start from $1,402. Find the lowest prices on one-way and return flight tickets right here.

Milan.$1,402 per passenger.Departing Sun, 2 Aug, returning Fri, 21 Aug.Return flight with Air France.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Sun, 2 Aug, arriving in Milan Malpensa.Inbound indirect flight with Air France, departs from Milan Malpensa on Fri, 21 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,402, select.

Rome.$1,431 per passenger.Departing Tue, 16 Feb, returning Sun, 28 Feb.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Tue, 16 Feb, arriving in Rome Fiumicino.Inbound indirect flight with Turkish Airlines, departs from Rome Fiumicino on Sun, 28 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,431, select.

Naples.$1,447 per passenger.Departing Fri, 11 Sep, returning Tue, 1 Dec.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Fri, 11 Sep, arriving in Naples International.Inbound indirect flight with Turkish Airlines, departs from Naples International on Tue, 1 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,447, select.

Bologna.$1,450 per passenger.Departing Mon, 14 Sep, returning Mon, 18 Jan.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 14 Sep, arriving in Bologna International.Inbound indirect flight with Turkish Airlines, departs from Bologna International on Mon, 18 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,450, select.

Venice.$1,451 per passenger.Departing Mon, 7 Sep, returning Sun, 13 Sep.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 7 Sep, arriving in Venice Marco Polo.Inbound indirect flight with Turkish Airlines, departs from Venice Marco Polo on Sun, 13 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,451, select.

Turin.$1,481 per passenger.Departing Mon, 30 Nov, returning Thu, 10 Dec.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Mon, 30 Nov, arriving in Turin.Inbound indirect flight with Turkish Airlines, departs from Turin on Thu, 10 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,481, select.

Catania.$1,628 per passenger.Departing Sat, 10 Oct, returning Sun, 18 Oct.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Sat, 10 Oct, arriving in Catania Fontanarossa.Inbound indirect flight with Turkish Airlines, departs from Catania Fontanarossa on Sun, 18 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,628, select.

Florence.$1,697 per passenger.Departing Thu, 15 Oct, returning Sun, 25 Oct.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Thu, 15 Oct, arriving in Florence.Inbound indirect flight with Air France, departs from Florence on Sun, 25 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,697, select.

Palermo.$2,113 per passenger.Departing Fri, 7 Aug, returning Mon, 17 Aug.Return flight with Air France and KLM.Outbound indirect flight with Air France, departs from Panama City Tocumen International on Fri, 7 Aug, arriving in Palermo.Inbound indirect flight with KLM, departs from Palermo on Mon, 17 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $2,113, select.

Cagliari.$2,138 per passenger.Departing Tue, 15 Sep, returning Tue, 29 Sep.Return flight with KLM.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Tue, 15 Sep, arriving in Cagliari.Inbound indirect flight with KLM, departs from Cagliari on Tue, 29 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $2,138, select.

Genoa.$2,503 per passenger.Departing Sat, 5 Sep, returning Mon, 14 Sep.Return flight with KLM and Air France.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Sat, 5 Sep, arriving in Genoa.Inbound indirect flight with Air France, departs from Genoa on Mon, 14 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $2,503, select.

Bari.$2,697 per passenger.Departing Sat, 29 Aug, returning Sat, 3 Oct.Return flight with Turkish Airlines.Outbound indirect flight with Turkish Airlines, departs from Panama City Tocumen International on Sat, 29 Aug, arriving in Bari.Inbound indirect flight with Turkish Airlines, departs from Bari on Sat, 3 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $2,697, select.

Pisa.$3,287 per passenger.Departing Fri, 7 Aug, returning Tue, 11 Aug.Return flight with KLM.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Fri, 7 Aug, arriving in Pisa International.Inbound indirect flight with KLM, departs from Pisa International on Tue, 11 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $3,287, select.

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Flights from Panama City to Italy FAQs

What is the cheapest flight to Italy from Panama City?

The cheapest flight from Panama City to Italy costs $1,402.

Explore the different prices of flights from Panama City to Italy and find the best option for you.

When is it the cheapest time to fly from Panama City to Italy?

The cheapest month to fly from Panama City to Italy is August. See if any of these flights in August suit you.

What is the cheapest Panama City to Italy flight route?

We've taken a look at the year ahead using our flights calendar. The cheapest flight route from Panama City to Italy is Panama City to Milan Malpensa. You can buy a ticket to fly this route from $1,402.

Take a look at Panama City to Milan Malpensa flights.

What is the cheapest airline that flies to Italy from Panama City?

Looking at the year ahead, the cheapest airline flying to Italy from Panama City is Air France.

Explore flight ticket options today.

Cheapest flights to Italy from Panama City

How to find cheap flights from Panama City to Italy

The cheapest return flight from Panama City to Italy is currently $1,402.
That fare gets you from Panama City into Milan Malpensa in Milan.
For one-way travel, the lowest price right now is $1,153.
Happy to go wherever the cheap flights are? Enter 'Italy' in the 'To' field to discover the lowest fares across different cities.
There's no shortage of ways to arrive in Italy, with around 35 airports to choose from.
Expand your search by choosing 'Add nearby airports.' This will compare prices across the closest airports at both your departure and destination points, which could help you find a better deal.
Book as early as possible. You'll have more airlines, routes and times to pick from. Leave it too long and you could be left with fewer choices and higher costs.
Easily track price changes by creating a Price Alert. Download the Skyscanner app (if you haven't already) to get updates instantly.

Best time to fly from Panama City to Italy

August is typically the cheapest month to hop on a flight from Panama City to Italy.
In general, travelling midweek can help you cut costs. Tuesdays and Wednesdays often mean cheaper fares.
June, July and August are the busiest months to travel to Italy. July leads the way, making it an ideal time to visit if you want the most going on.
January, February and March are quieter months. March has the lowest overall travel demand and is a good option if you prefer a more laid-back experience.

Popular places to visit in Italy

Milan

A leading destination for Panama City to Italy flights, this city in Lombardy lands at the top of the must-visit list. From Leonardo's Last Supper Museum and Teatro alla Scala to Milan Cathedral, the attractions come thick and fast.
Milan's major airports are Milan Malpensa Airport (MXP), Milan Bergamo Airport (BGY) and Milan Linate Airport (LIN). You'll find plenty of flight deals across all three.
Explore the selection of hotels in Milan and round out your trip with a stay you'll love.

Rome

Vatican Museums, St. Peter's Basilica and Vatican Hill are an ideal introduction to the highlights in this Lazio city.
Rome Fiumicino Airport (FCO) and Rome Ciampino Airport (CIA) are the main ways to fly in.
Browse hotels in Rome and lock in a stay that fits your travel plans.

Venice

Grand Canal, Centro Storico di Venezia and Saint Mark's Basilica are major attractions to tick off while you're in this part of Veneto.
The majority of travellers arrive through Venice Marco Polo Airport (VCE). You can also fly into Venice Treviso Airport (TSF).
Grab a deal on where you'll stay by checking out the list of hotels in Venice.

Visiting Italy for the first time? Here's what you need to know

Know the entry rules before you fly. Rules can vary depending on your passport, length of stay and reason for travel. Always check with official sources like your airline, the local embassy or your travel agent.
You'll be using the euro (EUR) for all your purchases. Debit and credit cards are widely accepted.
Italy has a population of around 59 million. The capital city is Rome.
You won't need to adjust your watch as you travel through this destination, with only one standard time zone of UTC+1 in place.
The weather can influence everything from sightseeing to packing, so travel when the forecast suits your plans. August is Italy's warmest month.
Conditions are often coolest around January.
Rainy days are more common in May, while July tends to be drier.
Some of the biggest events on the local calendar include Venice Carnival, the Venice Film Festival and the Infiorata flower festival. Line up your Panama City to Italy flight around occasions like these for an experience that goes beyond sightseeing.

Complete your trip with hotels and a car rental

A cheap flight from Panama City to Italy will get you there. Your next move is planning the stay. Discover competitive prices and exclusive rates for hotels in Italy. For the freedom to get around at your own pace, also check out the range of car rental options in Italy.

Italy hotels and car hire

Did you know we can help you plan the rest of your trip from Panama City to Italy? Get exclusive deals and great rates for hotels and car hire in Italy.