Cheap Flights from Antofagasta to Cali

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Flight deals from Antofagasta to Cali

Looking for a cheap last-minute deal or the best return flight from Antofagasta Airport to Cali Airport? If you want to travel next month, return fares start from $543. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Antofagasta to Cali

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Antofagasta to Cali flights are currently cheapest in September.

Direct flights from Antofagasta to Cali

Antofagasta to Cali: Alternative routes

Compare routes from Antofagasta to Cali below. You may find an airport to fly into that's cheaper, faster, or easier than Cali.

Antofagasta to Cali: Flight information

The things to know before you go.
Cheapest flight found$406
Cheapest month to flySeptember
Average flight time4 hrs, 38 mins
Most popular airlineJetSmart
Average flights per week5

Finding cheap flights from Antofagasta to Cali: Frequently asked questions

The best price we found for a return flight from Antofagasta to Cali is $406. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
4 hours and 38 minutes is the average flight time from Antofagasta to Cali.
JetSmart flies direct from Antofagasta to Cali.
As of June 2026, there are 5 flights per week flying from Antofagasta to Cali.
The cheapest month to fly from Antofagasta to Cali is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Antofagasta Airport to Cali Airport on Tuesday, 8 September 2026.
Yes – the average flight time is 4 hours and 38 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Cali but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Cali is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, JetSmart offers the cheapest flight tickets to Cali.

Travelling from Antofagasta Airport (ANF) to Cali Airport (CLO): what you need to know

  • The average time for a direct flight from Antofagasta Airport to Cali Airport is 3 hours 55 minutes.

  • Cali is two hours behind Antofagasta and is in the UTC-5 timezone.

  • Every week, there are four Antofagasta Airport to Cali Airport flights. To get going as early as possible, jump on the 09:32 JetSMART flight. If you'd rather make the most of your day before you fly, the last departure is at 09:32 with JetSMART.

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules to live by. Be at the airport on time to catch your ANF to CLO flight.

  • During popular months like June, it's a good idea to get to the airport even earlier. Arrive two hours before domestic departures and four hours ahead for an international flight when you fly during a high season in general.

  • JetSmart has direct flights from Antofagasta Airport to Cali Airport. Book with this popular carrier, then get ready to check out the sights in Cali — and maybe even more of Colombia if your schedule allows.

  • JetSmart is the most frequently booked airline on this route.

  • If you'd love to explore a new city along the way, look for a flight with a stopover. To see your options for tickets from Antofagasta Airport to Cali Airport, uncheck 'Direct flights only.' Santiago Arturo Merino Benitez Airport is a sought-after stop between ANF and CLO.

How to find the cheapest flights from Antofagasta Airport (ANF) to Cali Airport (CLO)

  • Currently, $151 is the lowest price we've seen for a one-way Antofagasta Airport to Cali Airport flight. The best price for a return ticket is $406. Remember that fares can change due to availability when booking.

  • To score cheap tickets from ANF to CLO, book your journey two months ahead of your planned departure.

  • The cheapest month for flights from Antofagasta Airport to Cali Airport is July. Use the 'Whole month' tool to see the lowest prices if you have a flexible schedule.

  • Snapping up cheap flights from ANF to CLO is easy with Price Alerts. All you need to do is set up one of these automatic alerts and we'll let you know when a lower fare pops up.

  • Tailor your trip with filters. Select your ideal arrival and departure times, airlines and total journey duration. You can also sort the results by 'Fastest,' 'Cheapest' or 'Best' flights from Antofagasta Airport to Cali Airport.

Handy information about Antofagasta Airport (ANF)

  • 86% of flights departing from Antofagasta Airport land at their destination on time. Given its strong performance rating, you're unlikely to face delays when flying out of ANF.

  • Antofagasta Airport is about 16 kilometres from central Antofagasta. If you're driving, ride-sharing or catching a taxi from the centre, it'll take 20 minutes or so to get there, depending on the traffic.

  • Expect a trip time of roughly 35 minutes on public transport.

  • Searching for a hotel to stay in before your flight from Antofagasta Airport to Cali Airport? Consider Hermoso Departamento con Laguna Navegable. Catch some z's here before making your way to ANF.

Arriving at Cali Airport (CLO)

  • Getting in late on a Antofagasta Airport to Cali Airport flight? Grab your luggage and head straight to the comfort of a nearby hotel. Two good options close to CLO are Hotel Real Elim International and Hotel Sin Escala.

  • Grab a Cali Airport rental car and discover Cali and beyond with your own set of wheels. Localiza, Alamo and Budget are top outlets you can book with here.

  • Secure the lowest price by reserving your ride from Cali Airport about two weeks ahead of your trip.

Getting from Cali Airport (CLO) to central Cali

  • Cali Airport to central Cali has a drive time of about 30 minutes. It's approximately 21 kilometres away.

  • It takes around 50 minutes to get there using public transport.

When to fly to Cali Airport (CLO)

  • January is the busiest month for flights from Antofagasta Airport to Cali Airport. To escape the crowds, go to Cali in March.

  • Lock in your flight from Antofagasta Airport to Cali Airport for September if you want to visit Cali during its warmest month. Expect temperatures of between 15ºC and 29ºC.

  • If you want cooler conditions, look for a cheap ticket from ANF to CLO in January. Temperatures average between 14ºC and 27ºC then.

Explore more of Colombia

  • Bogota is just one of the many cities in Colombia waiting to be discovered after you've experienced Cali. Around 306 kilometres away to the north-east, its best attractions include Teatro Colon Bogota, Park Simón Bolívar Bogotá City and Museum of Contemporary Art of Bogota.

  • If you're eager to discover another side of Colombia, consider Medellin, roughly 322 kilometres north of Cali. EcoParque Comuna 13, Palacio de Bellas Artes and Museo comuna 13 are among its highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.