Cheap Flights from Detroit Wayne County to Panama City

Compare Detroit Wayne County to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

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Flight deals from Detroit Wayne County to Panama City

Looking for a cheap last-minute deal or the best return flight from Detroit Wayne County Airport to Panama City? If you want to travel next month, return fares start from $1,331. Find the lowest prices on one-way and return tickets right here.

Panama City.$1,222 per passenger.Departing Tue, 1 Sep, returning Tue, 8 Sep.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Tue, 1 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 8 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,222, select.

Panama City.$1,268 per passenger.Departing Tue, 5 Jan, returning Fri, 5 Feb.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Tue, 5 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 5 Feb, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,268, select.

Panama City.$1,273 per passenger.Departing Mon, 23 Nov, returning Mon, 30 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Mon, 23 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 30 Nov, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,273, select.

Panama City.$1,273 per passenger.Departing Mon, 19 Oct, returning Mon, 2 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Mon, 19 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 2 Nov, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,273, select.

Panama City.$1,283 per passenger.Departing Sun, 17 Jan, returning Mon, 25 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Sun, 17 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 25 Jan, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,283, select.

Panama City.$1,331 per passenger.Departing Mon, 20 Jul, returning Wed, 29 Jul.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Mon, 20 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Wed, 29 Jul, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,331, select.

Panama City.$1,334 per passenger.Departing Thu, 13 Aug, returning Mon, 31 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Thu, 13 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 31 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,334, select.

Panama City.$1,437 per passenger.Departing Fri, 31 Jul, returning Sun, 9 Aug.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Fri, 31 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sun, 9 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,437, select.

Panama City.$1,461 per passenger.Departing Thu, 8 Apr, returning Mon, 12 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Thu, 8 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 12 Apr, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,461, select.

Panama City.$1,501 per passenger.Departing Thu, 4 Feb, returning Sun, 7 Feb.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 4 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sun, 7 Feb, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,501, select.

Panama City.$1,536 per passenger.Departing Mon, 8 Mar, returning Sat, 13 Mar.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Mon, 8 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sat, 13 Mar, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,536, select.

Panama City.$1,543 per passenger.Departing Fri, 16 Oct, returning Mon, 19 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Fri, 16 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Mon, 19 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,543, select.

Panama City.$1,568 per passenger.Departing Thu, 18 Jun, returning Thu, 25 Jun.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 18 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Thu, 25 Jun, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,568, select.

Panama City.$1,572 per passenger.Departing Fri, 26 Jun, returning Fri, 3 Jul.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Fri, 26 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 3 Jul, arriving in Detroit Wayne County.Price includes taxes and charges.From $1,572, select.

Panama City.$2,080 per passenger.Departing Wed, 16 Dec, returning Tue, 22 Dec.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Wed, 16 Dec, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 22 Dec, arriving in Detroit Wayne County.Price includes taxes and charges.From $2,080, select.

Find the cheapest month to fly from Detroit Wayne County to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Detroit Wayne County to Panama City flights are currently cheapest in September.

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Alternative Detroit Wayne County to Panama City routes

Looking for the cheapest, fastest or easiest route from Detroit Wayne County to Panama City? You could fly into the following airports instead.

Detroit to Panama City: Flight information

The things to know before you go.

Cheapest flight found	$1,222
Cheapest month to fly	September

Finding cheap flights from Detroit Wayne County to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Detroit Wayne County to Panama City?

The best price we found for a return flight from Detroit Wayne County to Panama City is $1,222. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Detroit Wayne County to Panama City?

Currently, there are no airlines that fly direct from Detroit Wayne County to Panama City. But we found flights with one or more stops from $1,222.

How many flights are there a week from Detroit Wayne County to Panama City?

As of June 2026, there are no flights flying from Detroit Wayne County to Panama City.

When is the cheapest time to fly from Detroit Wayne County to Panama City?

The cheapest month to fly from Detroit Wayne County to Panama City is usually September.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Detroit Wayne County Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $1,222.

Which upcoming date is cheapest to fly from Detroit Wayne County Airport to Panama City on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Detroit Wayne County Airport to Panama City on Tuesday, 1 September 2026.

Can I get a direct flight from Detroit Wayne County Airport to Panama City?

No airlines currently offer direct flights between Detroit Wayne County Airport and Panama City. Most routes have one or more stops.

How can I get the best flight deal from Detroit Wayne County Airport to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In June, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Detroit Wayne County Airport to Panama City with?

Currently, United offers the cheapest flight tickets to Panama City.

Flying from Detroit Metropolitan Wayne County Airport (DTW) to Panama City: what you need to know

Detroit (the location of Detroit Metropolitan Wayne County Airport) and Panama City share the same timezone — UTC-5.
Leave enough time to make your DTW to Panama City flight. As a general rule, arrive two hours before international departures and an hour ahead for domestic flights.
Flying over a peak time such as July? Public holidays and other popular periods can lead to longer queues at security. Be extra cautious and arrive up to four hours ahead of an international flight and two hours before domestic departures.
We make it a breeze to book plane tickets from DTW to Panama City with a stopover. To see all your options, deselect 'Direct flights only.' Next, select a flight offering a stop long enough to tour your chosen city. Major stopovers include:
- Miami International Airport (MIA)
- Orlando International Airport (MCO)
- Cancun International Airport (CUN)
DTW is about 29 kilometres from central Detroit. If you're catching a taxi, ride-sharing or driving from the centre, it'll take 30 minutes or so to get there, depending on the traffic. If you're using public transport, expect the trip time to be around 1 hour.
Want a hassle-free start to your holiday? Stay near DTW. Whether you've booked an early flight from Detroit Metropolitan Wayne County Airport to Panama City or want to avoid feeling rushed, these hotels are just the thing:
Of all flights departing from Detroit Metropolitan Wayne County Airport, 74% arrive on time at their destination.
DTW is located at 1 Detroit Metro Airport.

How to find the cheapest flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City

$664 is currently the lowest price for a one-way Detroit Metropolitan Wayne County Airport to Panama City flight. A return plane ticket starts from $1,222. These prices may change depending on availability and demand.
To pick up cheap flights from DTW to Panama City, book ahead. Airlines generally offer lower prices when tickets are first released.
The 'Whole month' tool will show you the cheapest tickets from Detroit Metropolitan Wayne County Airport to Panama City across each month. It's a great way to find a bargain if your trip dates aren't set in stone.
Cut down on the time spent looking for cheap flights from DTW to Panama City by setting up a Price Alert. You'll get an email or notification on the app when a new discounted fare appears.
Snag an affordable flight from Detroit Metropolitan Wayne County Airport to Panama City with the help of our filters. Select your preferred times, airlines and number of stops, then sort the results by 'Cheapest' to see the best deals.

Airports in Panama City

Panama City Tocumen International Airport (PTY)

Panama City Tocumen International Airport (PTY) to the centre of Panama City takes about 35 minutes to reach by car. The centre is roughly 24 kilometres away.
It'll take around 50 minutes if you're using public transport.
The last thing you want is a long journey to your hotel if you're arriving on a late flight from Detroit Metropolitan Wayne County Airport to Panama City. Check in to one of these accommodation options near PTY instead:
Booking your ride from Panama City Tocumen International Airport about three weeks in advance of your flight from DTW to Panama City can help you get the lowest rate.

Panama Pacifico International Airport (BLB)

Panama Pacifico International Airport (BLB) is around 6 kilometres from central Panama City. After your flight from Detroit Metropolitan Wayne County Airport to Panama City, it'll take you around 10 minutes to reach the heart of the city in a taxi or ride-share.
If you're travelling on public transport, it'll take about 20 minutes.
After stepping off your DTW to Panama City flight, tuck yourself in at a hotel close to BLB. These are some comfortable options that'll help you slip into relaxation mode:
Snap up a deal by reserving your ride from BLB one week in advance. You can also expect to have a greater selection of vehicles.

Best time to go to Panama City

January is the busiest month for flights from Detroit Metropolitan Wayne County Airport to Panama City. To avoid the crowds, plan your trip to Panama City in September.
Book a Detroit Metropolitan Wayne County Airport to Panama City plane ticket with a departure in March if you're eager to visit the city during its warmest month. Expect temperatures to range from 21ºC to 32ºC.
Search for cheap tickets from DTW to Panama City in January if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 22ºC and 31ºC on average.

More about Panama City

When it comes to searching for somewhere to rest your head, you'll find the top stays in Panama City right here. Check out these hotels as soon as you've locked in your flight from Detroit Metropolitan Wayne County Airport to Panama City:
Every great journey has to include some sightseeing. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are must-do's during your Panama City adventure.

Explore more of Panama

Panama City is easy to fall in love with, but there are so many other parts of Panama waiting to be discovered. Around 322 kilometres west of Panama City, a trip to David will keep you busy. Check out popular attractions like Museo Antropológico y Etnográfico Dr. Roberto De La Guardia, Raptors To The Rescue and Unachi Botanical garden.
Where to next? Head off for Santiago de Veraguas. It's around 193 kilometres southwest of Panama City and boasts highlights like Santiago the Apostle Cathedral, Santiago de Veraguas.