Cheap Flights from Guayaquil to Santiago

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      Compare Guayaquil to Santiago flight deals

      Find the cheapest month or even day of the year to fly to Santiago

      Book the best Santiago fare with no extra fees

      Flight deals from Guayaquil to Santiago

      Looking for a cheap last-minute deal or the best return flight from Guayaquil to Santiago? Find the lowest prices on one-way and return tickets right here.

      Find the cheapest month to fly from Guayaquil to Santiago

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Guayaquil to Santiago flights are currently cheapest in April.

      Guayaquil to Santiago: Alternative routes

      Compare routes from Guayaquil to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

      Guayaquil to Santiago: Flight information

      The things to know before you go.
      Cheapest flight found$902
      Cheapest month to flyApril

      Finding cheap flights from Guayaquil to Santiago: Frequently asked questions

      The best price we found for a return flight from Guayaquil to Santiago is $902. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Guayaquil to Santiago. But we found flights with one or more stops from $902.
      As of September 2026, there are no flights flying from Guayaquil to Santiago.
      The cheapest month to fly from Guayaquil to Santiago is usually April.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Guayaquil Airport to Santiago Airport on Thursday, 1 April 2027.
      No airlines currently offer direct flights between Guayaquil Airport and Santiago Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Copa offers the cheapest flight tickets to Santiago.

      Travelling from Guayaquil Airport (GYE) to Santiago Airport (STI): what you need to know

      • Santiago is one hour ahead of Guayaquil and observes the UTC-4 timezone.

      • For a stress-free journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This will give you enough time to board your GYE to STI flight.

      • During popular months like July, it's a good idea to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead for an international flight when you travel during peak periods in general.

      • We make it a cinch to book a flight with a stopover. To see your options for tickets from Guayaquil Airport to Santiago Airport, uncheck 'Direct flights only.' Then, pick a flight with a stop long enough to visit your chosen city. Worthwhile stopovers between GYE and STI include:

        • New York John F. Kennedy Airport

        • Panama City Tocumen International Airport

        • Santo Domingo Las Americas Airport

      How to find the cheapest flights from Guayaquil Airport (GYE) to Santiago Airport (STI)

      • The cheapest price we've seen for a one-way Guayaquil Airport to Santiago Airport flight is $1,530. A round-trip fare right now is $902. Depending on the availability when you book, these fares can change.

      • To pick up cheap tickets from GYE to STI, book early. Airlines tend to offer their best fares when flights are first made available.

      • If you can be flexible with your travel dates, use the 'Whole month' tool. It'll give you the lowest price across the month when searching for a flight from Guayaquil Airport to Santiago Airport.

      • Finding cheap flights from GYE to STI is a cinch with Price Alerts. All you need to do is set up one of these automatic alerts and we'll notify you when a new discounted fare appears.

      • Tailor your flights with filters. Choose your arrival and departure times, airlines and total journey duration. You can also sort your results by 'Best,' 'Fastest' or 'Cheapest' flights from Guayaquil Airport to Santiago Airport.

      Handy information about Guayaquil Airport (GYE)

      • Guayaquil Airport gets top marks for on-time performance. 90% of flights that take off from GYE reach their destination on time.

      • To reach Guayaquil Airport from central Guayaquil, it takes around 20 minutes if you're travelling by car. Of course, this depends on traffic conditions. It's approximately 8 kilometres from the airport to the city centre.

      • You can expect a trip time of around 35 minutes on public transport.

      • Get your trip off to a stress-free start by staying near GYE. Whether you're catching an early flight from Guayaquil Airport to Santiago Airport or just don't like being rushed, these hotels are ideal:

      Arriving at Santiago Airport (STI)

      • If you have a late Guayaquil Airport to Santiago Airport flight, few things top the convenience of staying near the terminal. Pick up your bags from the carousel and then be showered and relaxing not long after at one of these hotels near STI:

      • Pick up a Santiago Airport rental car and discover Santiago and beyond with your own set of wheels. America, Zezgo Rent a Car and Alamo are leading providers you can book with here.

      • To lock in the lowest price, reserve your vehicle from Santiago Airport about one week before you set off.

      Getting from Santiago Airport (STI) to central Santiago

      • From Santiago Airport, Santiago is approximately 16 kilometres away. It takes around 25 minutes to reach the centre by car.

      • When travelling by public transport, expect a journey of around 40 minutes.

      When to fly to Santiago Airport (STI)

      • It's time to work out your trip dates for your flight from Guayaquil Airport to Santiago Airport. August is the busiest month to visit Santiago. If you prefer a more laid-back vibe, go in October.

      • Lock in your flight from Guayaquil Airport to Santiago Airport for August if you'd like to explore Santiago during its warmest month. Expect temperatures of between 21ºC and 33ºC.

      • January has average temperatures of between 16ºC and 29ºC. Search for cheap tickets from GYE to STI sometime then if you want to travel in cooler conditions.

      Explore more of the Dominican Republic

      • Santo Domingo is just one of the many places in the Dominican Republic waiting to be explored after you've experienced Santiago. Around 137 kilometres away to the south-east, popular attractions include Catedral Primada de las Americas, Alcazar de Colon and The Cathedral of the Americas.

      • If you want to check out another great destination in the Dominican Republic, consider Santo Domingo Este, roughly 145 kilometres south-east of Santiago. Lago los tres ojos, National Aquarium and La Cueva del Eden are among the biggest draws.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.