Cheap Flights from Medellin to Sao Paulo

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Compare Medellin to Sao Paulo flight deals

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Flight deals from Medellin to Sao Paulo

Looking for a cheap last-minute deal or the best return flight from Medellin to Sao Paulo? If you want to travel next month, return fares start from $742. Find the lowest prices on one-way and return tickets right here.

Sao Paulo.$743 per passenger.Departing Thu, 24 Sep, returning Thu, 1 Oct.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Thu, 24 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Thu, 1 Oct, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $743, select.

Sao Paulo.$746 per passenger.Departing Wed, 28 Oct, returning Mon, 2 Nov.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Wed, 28 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Mon, 2 Nov, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $746, select.

Sao Paulo.$748 per passenger.Departing Thu, 24 Sep, returning Tue, 29 Sep.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Thu, 24 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Tue, 29 Sep, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $748, select.

Sao Paulo.$749 per passenger.Departing Fri, 11 Sep, returning Wed, 25 Nov.Return flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Fri, 11 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Copa, departs from Sao Paulo Guarulhos on Wed, 25 Nov, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $749, select.

Sao Paulo.$749 per passenger.Departing Fri, 2 Oct, returning Fri, 16 Oct.Return flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Fri, 2 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Copa, departs from Sao Paulo Guarulhos on Fri, 16 Oct, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $749, select.

Sao Paulo.$749 per passenger.Departing Sun, 15 Nov, returning Fri, 27 Nov.Return flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Sun, 15 Nov, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Copa, departs from Sao Paulo Guarulhos on Fri, 27 Nov, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $749, select.

Sao Paulo.$812 per passenger.Departing Mon, 30 Nov, returning Sun, 6 Dec.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Mon, 30 Nov, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Sun, 6 Dec, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $812, select.

Sao Paulo.$835 per passenger.Departing Wed, 17 Feb, returning Thu, 25 Feb.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Wed, 17 Feb, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Thu, 25 Feb, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $835, select.

Sao Paulo.$844 per passenger.Departing Mon, 22 Mar, returning Tue, 20 Apr.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Mon, 22 Mar, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Tue, 20 Apr, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $844, select.

Sao Paulo.$846 per passenger.Departing Fri, 2 Apr, returning Fri, 16 Apr.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Fri, 2 Apr, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Fri, 16 Apr, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $846, select.

Sao Paulo.$856 per passenger.Departing Tue, 2 Feb, returning Sun, 4 Apr.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Tue, 2 Feb, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Sun, 4 Apr, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $856, select.

Sao Paulo.$862 per passenger.Departing Sun, 21 Mar, returning Thu, 25 Mar.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Sun, 21 Mar, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Thu, 25 Mar, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $862, select.

Sao Paulo.$867 per passenger.Departing Tue, 1 Dec, returning Sun, 6 Dec.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Tue, 1 Dec, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Sun, 6 Dec, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $867, select.

Sao Paulo.$875 per passenger.Departing Tue, 23 Feb, returning Tue, 2 Mar.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Tue, 23 Feb, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Tue, 2 Mar, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $875, select.

Sao Paulo.$886 per passenger.Departing Wed, 28 Apr, returning Tue, 4 May.Return flight with Copa.Outbound indirect flight with Copa, departs from Medellin Jose Maria Cordova on Wed, 28 Apr, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Copa, departs from Sao Paulo Guarulhos on Tue, 4 May, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $886, select.

Sao Paulo.$897 per passenger.Departing Thu, 21 Jan, returning Sat, 13 Feb.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Medellin Jose Maria Cordova on Thu, 21 Jan, arriving in Sao Paulo Guarulhos.Inbound indirect flight with LATAM Airlines, departs from Sao Paulo Guarulhos on Sat, 13 Feb, arriving in Medellin Jose Maria Cordova.Price includes taxes and charges.From $897, select.

Find the cheapest month to fly from Medellin to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Medellin to Sao Paulo flights are currently cheapest in September.

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Alternative Medellin to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Medellin to Sao Paulo? You could fly into the following airports instead.

Medellin to Sao Paulo: Flight information

The things to know before you go.

Cheapest flight found	$743
Cheapest month to fly	September

Finding cheap flights from Medellin to Sao Paulo: Frequently asked questions

How many airports are there in Sao Paulo?

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.

How much are return flights from Medellin to Sao Paulo?

The best price we found for a return flight from Medellin to Sao Paulo is $743. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Medellin to Sao Paulo?

Currently, there are no airlines that fly direct from Medellin to Sao Paulo. But we found flights with one or more stops from $736.

How many flights are there a week from Medellin to Sao Paulo?

As of September 2026, there are no flights flying from Medellin to Sao Paulo.

When is the cheapest time to fly from Medellin to Sao Paulo?

The cheapest month to fly from Medellin to Sao Paulo is usually September.

Which is the cheapest airport to fly into in Sao Paulo?

If you're flying from Medellin, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the centre of Sao Paulo. We've found flights into this airport from $743.

Which upcoming date is cheapest to fly from Medellin to Sao Paulo on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Medellin to Sao Paulo on Thursday, 24 September 2026.

Can I get a direct flight from Medellin to Sao Paulo?

No airlines currently offer direct flights between Medellin and Sao Paulo. Most routes have one or more stops.

How can I get the best flight deal from Medellin to Sao Paulo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Sao Paulo?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Sao Paulo?

In September, the average temperature is usually around 21°C. January is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in July. The coldest month is June, with temperatures averaging 13°C. The rainiest month is January.

Which is the cheapest airline to fly from Medellin to Sao Paulo with?

The cheapest airline that flies to Sao Paulo is LATAM Airlines .

Travelling from Medellin to Sao Paulo: what you need to know

Medellin's main base, Medellin Jose Maria Cordova Airport (MDE), is where plenty of awesome adventures begin. Explore the departure options from here when planning your flight from Medellin to Sao Paulo.
Sao Paulo Guarulhos Airport (GRU) and Sao Paulo Viracopos Airport (VCP) are Sao Paulo's chief entry points.
Sao Paulo's timezone is UTC-3, making Sao Paulo two hours ahead of Medellin.
For a smooth journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. That way, you won't have to rush to catch your Medellin to Sao Paulo flight.
During popular months like December, you'll want to get to the airport earlier than usual. Arrive two hours before domestic departures and four hours ahead of international flights when you travel during peak periods in general.

How to find the cheapest flights from Medellin to Sao Paulo

Don't wait until the last moment. You're more likely to find cheap Medellin to Sao Paulo flights if you book in advance. Airlines often offer some excellent early bird discounts.
If you're flexible with your travel plans, try using the 'Whole month' search tool. It'll give you the lowest price across every month when looking for your plane ticket from Medellin to Sao Paulo.
There's no need to check every day to find out if fares have dropped when you set up a Price Alert. We'll notify you the moment a better deal comes up on cheap flights from Medellin to Sao Paulo.
Find an affordable Medellin to Sao Paulo flight with the help of our filters. Select your ideal departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Medellin

Medellin Jose Maria Cordova Airport (MDE)

Consider adding a stopover to possibly find a cheaper Medellin to Sao Paulo flight. Just uncheck 'Direct flights only' when searching for departures from Medellin Jose Maria Cordova Airport. Take a pause at one of these popular airports:
- Bogota Airport (BOG)
- Lima Airport (LIM)
- Panama City Tocumen International Airport (PTY)
The journey from central Medellin to MDE takes about 1 hour 15 minutes by public transport. If you ride-share, drive or get a taxi, you'll cover the 18 kilometres in 45 minutes or so, depending on traffic conditions.
Want a leisurely start to your trip? Stay near Medellin Jose Maria Cordova Airport. Whether you're catching an early flight from Medellin to Sao Paulo or just don't like being rushed, these hotels are ideal:
When it comes to Medellin Jose Maria Cordova Airport's on-time performance, 76% of flights arrive within the scheduled time frame.

Arriving in Sao Paulo

Sao Paulo Guarulhos Airport (GRU)

The distance from Sao Paulo Guarulhos Airport (GRU) to central Sao Paulo is roughly 21 kilometres. It'll take you about 45 minutes to get to the centre driving.
When travelling on public transport, expect a journey time of around 1 hour 10 minutes.
Consider booking a hotel near GRU if you're coming in on a late flight from Medellin to Sao Paulo. Choose one of these options and avoid the hassle of a long transfer:
Get on the fast track to adventure by picking up a Sao Paulo Guarulhos Airport rental car. Grab your wheels from Foco, Localiza or Movida and explore beyond Sao Paulo's main sights.
Lock in the best deal by reserving your ride from Sao Paulo Guarulhos Airport about two weeks before your departure date.

Sao Paulo Congonhas Airport (CGH)

The centre of Sao Paulo is about 8 kilometres from Sao Paulo Congonhas Airport (CGH). Once your flight from Medellin to Sao Paulo has landed and you've made your way to arrivals, expect a drive of about 25 minutes.
If you're catching public transport, it'll take around 50 minutes.
You'll find some great places ready to welcome you near CGH. Settle in and get cosy after your Medellin to Sao Paulo flight at one of these well-located options:
The fastest way to get to where you're going is with a Sao Paulo Congonhas Airport rental car. Collect a set of wheels from Foco, Localiza or Movida and make a speedy getaway.
Lock in the best price by booking your ride from CGH three weeks in advance. You can also expect to have a bigger selection of vehicles.

Sao Paulo Viracopos Airport (VCP)

Sao Paulo Viracopos Airport (VCP) is roughly 80 kilometres from the centre of Sao Paulo. It'll take you about 1 hour 30 minutes to reach the city centre by taxi or ride-share once you've stepped off your flight from Medellin to Sao Paulo.
Public transport will take you there in around 2 hours 20 minutes.
Begin your journey without stressing about how to get to your destination with a Sao Paulo Viracopos Airport rental car. Book your wheels with reliable suppliers here like Foco, Localiza and Movida.
If you're looking for a specific type of vehicle, lock in your ride from VCP around four weeks before your flight from Medellin to Sao Paulo. This gives you a better chance of getting the car you want, on top of a better deal.

Best time to go to Sao Paulo

March is the quietest month for flights from Medellin to Sao Paulo, while July is the most popular. Figure out the best time to go to Sao Paulo based on whether you prefer a lively atmosphere or a more laid-back vibe.
When booking your Medellin to Sao Paulo tickets, think about the weather you're most comfortable in. February is the warmest month in Sao Paulo, with temperatures ranging from 18ºC to 29ºC.
July sees average temperatures of between 12ºC and 25ºC. Look for cheap flights from Medellin to Sao Paulo around that time if you like travelling in cooler conditions.

More about Sao Paulo

Start your Sao Paulo trip right by choosing the ideal place to stay. Once you've booked your flight from Medellin to Sao Paulo, explore our selection of hotels including:
Every great adventure has to include some sightseeing. Ibirapuera Park, Av. Paulista and Pinacoteca Do Estado De Sao Paulo are essential stops on your Sao Paulo itinerary.

Explore more of Brazil

Sao Paulo will leave a lasting impression, but there are so many other corners of Brazil waiting to be discovered. Around 499 kilometres northeast of Sao Paulo, a visit to Belo Horizonte will keep you on the go. Start with popular sights like Pampulha Modern Ensemble, Casa do Baile and Igreja São Francisco de Assis.
If you want to check out another major destination in Brazil, consider Curitiba, about 338 kilometres southwest of Sao Paulo. Oscar Niemeyer Museum, Eco Park and Botanical Garden of Curitiba are the start of reasons to visit.