Cheap Flights from Pittsburgh International to Knoxville

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Compare Pittsburgh International to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Pittsburgh International to Knoxville

Looking for a cheap last-minute deal or the best return flight from Pittsburgh International Airport to Knoxville Airport? If you want to travel next month, return fares start from $456. Find the lowest prices on one-way and return tickets right here.

Knoxville.$456 per passenger.Departing Mon, 21 Sep, returning Mon, 28 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Mon, 21 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 28 Sep, arriving in Pittsburgh International.Price includes taxes and charges.From $456, select.

Knoxville.$457 per passenger.Departing Sat, 5 Dec, returning Tue, 5 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Sat, 5 Dec, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 5 Jan, arriving in Pittsburgh International.Price includes taxes and charges.From $457, select.

Knoxville.$457 per passenger.Departing Thu, 14 Jan, returning Mon, 18 Jan.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Thu, 14 Jan, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 18 Jan, arriving in Pittsburgh International.Price includes taxes and charges.From $457, select.

Knoxville.$478 per passenger.Departing Mon, 5 Oct, returning Fri, 9 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Mon, 5 Oct, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Fri, 9 Oct, arriving in Pittsburgh International.Price includes taxes and charges.From $478, select.

Knoxville.$550 per passenger.Departing Fri, 9 Apr, returning Sat, 17 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Fri, 9 Apr, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 17 Apr, arriving in Pittsburgh International.Price includes taxes and charges.From $550, select.

Knoxville.$550 per passenger.Departing Sat, 6 Mar, returning Sat, 13 Mar.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Sat, 6 Mar, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 13 Mar, arriving in Pittsburgh International.Price includes taxes and charges.From $550, select.

Knoxville.$632 per passenger.Departing Fri, 2 Jul, returning Tue, 6 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Fri, 2 Jul, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 6 Jul, arriving in Pittsburgh International.Price includes taxes and charges.From $632, select.

Knoxville.$663 per passenger.Departing Thu, 24 Sep, returning Thu, 1 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Thu, 24 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Thu, 1 Oct, arriving in Pittsburgh International.Price includes taxes and charges.From $663, select.

Knoxville.$674 per passenger.Departing Fri, 11 Dec, returning Fri, 18 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Fri, 11 Dec, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Fri, 18 Dec, arriving in Pittsburgh International.Price includes taxes and charges.From $674, select.

Knoxville.$785 per passenger.Departing Thu, 19 Nov, returning Sat, 28 Nov.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Pittsburgh International on Thu, 19 Nov, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Sat, 28 Nov, arriving in Pittsburgh International.Price includes taxes and charges.From $785, select.

Knoxville.$1,090 per passenger.Departing Fri, 28 Aug, returning Mon, 31 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Pittsburgh International on Fri, 28 Aug, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 31 Aug, arriving in Pittsburgh International.Price includes taxes and charges.From $1,090, select.

Find the cheapest month to fly from Pittsburgh International to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Pittsburgh International to Knoxville flights are currently cheapest in September.

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Pittsburgh International to Knoxville: Alternative routes

Compare routes from Pittsburgh International to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville

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from $456

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Pittsburgh to Knoxville: Flight information

The things to know before you go.

Cheapest flight found	$456
Cheapest month to fly	September

Finding cheap flights from Pittsburgh International to Knoxville: Frequently asked questions

How much are return flights from Pittsburgh International to Knoxville?

The best price we found for a return flight from Pittsburgh International to Knoxville is $456. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Pittsburgh International to Knoxville?

Currently, there are no airlines that fly direct from Pittsburgh International to Knoxville. But we found flights with one or more stops from $456.

How many flights are there a week from Pittsburgh International to Knoxville?

As of August 2026, there are no flights flying from Pittsburgh International to Knoxville.

When is the cheapest time to fly from Pittsburgh International to Knoxville?

The cheapest month to fly from Pittsburgh International to Knoxville is usually September.

Which upcoming date is cheapest to fly from Pittsburgh International Airport to Knoxville Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Pittsburgh International Airport to Knoxville Airport on Monday, 21 September 2026.

Can I get a direct flight from Pittsburgh International Airport to Knoxville Airport?

No airlines currently offer direct flights between Pittsburgh International Airport and Knoxville Airport. Most routes have one or more stops.

How can I find the best flight deal to Knoxville?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Knoxville?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Pittsburgh International Airport to Knoxville with?

Currently, Delta offers the cheapest flight tickets to Knoxville.

Travelling from Pittsburgh International Airport (PIT) to Knoxville Airport (TYS): what you need to know

Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for hassle-free flying. Show up at the airport on time to board your PIT to TYS flight.
During popular months like July, you'll want to get to the airport even earlier. Plan to arrive two hours before domestic departures and four hours ahead of international flights whenever you're travelling during peak periods in general.
If you'd like to break up your flight, simply deselect 'Direct flights only' when searching for your ticket from Pittsburgh International Airport to Knoxville Airport. Here are the most popular stopovers between PIT and TYS:
- Atlanta Hartsfield-Jackson Airport
- Charlotte Douglas Airport
- Philadelphia International Airport

How to find the cheapest flights from Pittsburgh International Airport (PIT) to Knoxville Airport (TYS)

$228 is the lowest price for a one-way Pittsburgh International Airport to Knoxville Airport flight. Return flights start from $456. These fares may change based on demand.
To get your hands on cheap tickets from PIT to TYS, book ahead. Airlines typically offer lower fares when flights are first released.
If you can be flexible with your trip dates, use the 'Whole month' search function. It'll give you the cheapest price across each month when searching for a flight from Pittsburgh International Airport to Knoxville Airport.
Landing cheap flights from PIT to TYS is a piece of cake with Price Alerts. All you need to do is create one of these automatic alerts and we'll notify you as soon as a new discounted fare appears.
Tailor your flights using filters. Select your ideal departure and arrival times, total journey duration and airlines. You can also sort the results by 'Cheapest,' 'Best' or 'Fastest' flights from Pittsburgh International Airport to Knoxville Airport.

Handy information about Pittsburgh International Airport (PIT)

You'll find PIT at 1000 Airport Boulevard.
Of the flights that depart from Pittsburgh International Airport, 77% arrive as scheduled at their destination.
To get to Pittsburgh International Airport from central Pittsburgh, it'll take about 30 minutes by car. Of course, this depends on traffic. It's approximately 32 kilometres from the airport to the city centre.
Expect a trip time of about 45 minutes on public transport.
Get your journey off to a hassle-free start by staying near PIT. Whether you're boarding an early flight from Pittsburgh International Airport to Knoxville Airport or just don't like being rushed, these hotels are ideal:

Arriving at Knoxville Airport (TYS)

Consider staying in a hotel near TYS if you're taking a late Pittsburgh International Airport to Knoxville Airport flight. Pick one of these accommodation options and skip the long transfer:
Get on the fast track to adventure by picking up a Knoxville Airport rental car. Grab your wheels from Budget, Alamo or Avis and experience the lesser-explored corners of Knoxville and beyond.
Reserving your vehicle from Knoxville Airport around three weeks ahead increases your chances of getting a good deal.

Getting from Knoxville Airport (TYS) to central Knoxville

TYS is located at 2055 Alcoa Highway.
Knoxville Airport to central Knoxville has a drive time of about 25 minutes. It's approximately 24 kilometres away.
It takes roughly 50 minutes when travelling by public transport.

When to fly to Knoxville Airport (TYS)

The quietest month for a flight from Pittsburgh International Airport to Knoxville Airport is March, while October is the most popular. Choose the best time to go to Knoxville based on whether you prefer a faster pace or a more relaxed vibe.
The warmest month in Knoxville is July, with temperatures ranging between 17ºC and 32ºC. Book your flights from Pittsburgh International Airport to Knoxville Airport in this month if this is the type of weather you enjoy.
If you want to travel in cooler conditions, search for a cheap ticket from PIT to TYS in January. Average temperatures are between -6ºC and 11ºC then.

Explore more of the United States

Columbus is just one of the many places in the United States waiting to be explored once you've seen Knoxville. Around 451 kilometres away to the north, well-known attractions include Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.
Indianapolis is another must-experience destination in the United States and is around 467 kilometres north-west of Knoxville. No trip is complete without dropping by Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.