Cheap Flights from Pisa International to Brussels

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Flight deals from Pisa International Airport to Brussels

Looking for a cheap last-minute deal or the best return flight from Pisa International Airport to Brussels? If you want to travel next month, return fares start from $81. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Pisa International to Brussels

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Pisa International to Brussels flights are currently cheapest in April.

Direct flights from Pisa International to Brussels

Pisa to Brussels: Flight information

The things to know before you go.
Cheapest flight found$34
Cheapest month to flyApril
Average flight time1 hr, 47 mins
Most popular airlineRyanair
Average flights per week23

Finding cheap flights from Pisa International to Brussels: Frequently asked questions

There are 5 airports in Brussels: Brussels International, Antwerp Deurne, Brussels S. Charleroi, Liege, and Kortrijk.
The best price we found for a return flight from Pisa International to Brussels is $69. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 46 minutes is the average flight time from Pisa International to Brussels.
Ryanair and Malta Air fly direct from Pisa International to Brussels.
As of April 2026, there are 23 flights per week flying from Pisa International to Brussels.
The cheapest month to fly from Pisa International to Brussels is usually April.
If you're flying from Pisa International Airport, the cheapest airport near Brussels is Brussels S. Charleroi – which is 44.1 km away from the centre of Brussels. We've found flights into this airport from $69.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Pisa International Airport to Brussels on Tuesday, 14 April 2026.
Yes – the average flight time is 1 hour and 46 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Brussels but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Brussels is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 9°C. July is typically the warmest month in Brussels, when it usually averages around 22°C. You can expect the least rain in April. The coldest month is January, with temperatures averaging -0°C. The rainiest month is December.
Currently, Ryanair offers the cheapest flight tickets to Brussels.

Flying from Pisa International Airport (PSA) to Brussels: what you need to know

  • Approximately 1 hour 45 minutes is how long you can expect to be in the air on a direct flight from Pisa International Airport to Brussels.

  • Brussels's timezone is UTC+1, which is the same as Pisa (the location of Pisa International Airport).

  • With 13 flights a week between the two airports, Pisa International Airport (PSA) to Brussels S. Charleroi Airport (CRL) is the busiest route. Ryanair operates the earliest flight at 06:00. If you prefer to make the most of your day before jetting off, the latest flight from PSA to CRL is with Ryanair at 20:40.

  • For stress-free travel, turn up at the airport two hours ahead of international flights and one hour before domestic departures. That way, you won't have to rush to catch your PSA to Brussels flight.

  • Be prepared for longer lines in popular months such as July. Arriving up to four hours ahead of an international flight and two hours for a domestic departure is a smart move.

  • Begin your trip at PSA and travel straight to Brussels Airport (BRU). That's where you can expect to land when searching for Pisa International Airport to Brussels tickets.

  • Ryanair is a popular airline that offers direct flights from Pisa International Airport to Brussels.

  • Consider adding a stopover to potentially score a cheaper plane ticket from PSA to Brussels. All you need to do is uncheck 'Direct flights only' during your search. Break up your journey by stopping at one of these connection hubs:

    • Frankfurt Airport (FRA)

    • Barcelona-El Prat Airport (BCN)

    • Manchester Airport (MAN)

  • Located around 5 kilometres from the centre of Pisa, PSA can be reached in about 15 minutes by car, depending on traffic. The journey on public transport takes roughly 45 minutes.

  • Looking for a hotel close to PSA? If you're catching an early flight from Pisa International Airport to Brussels, these accommodation options put the terminal practically at your doorstep:

  • 73.71% of flights departing from Pisa International Airport touch down at their destination on schedule.

How to find the cheapest flights from Pisa International Airport (PSA) to Brussels

  • $34 is the lowest price we've found for a one-way Pisa International Airport to Brussels flight. A round-trip ticket right now is $69. Depending on when and how early you book, these fares could change.

  • Don't leave things to the last moment. You're more likely to land cheap flights from PSA to Brussels if you book ahead. Airlines often have some amazing early bird deals.

  • Finding cheap tickets from Pisa International Airport to Brussels is easier if you can be flexible with your trip dates. Try using the 'Whole month' search tool to access the lowest prices across every month and score an awesome deal.

  • There's no need to check every day to see if fares have dropped when you create a Price Alert. We'll let you know as soon as there's an even better deal on cheap flights from PSA to Brussels.

  • Tailor your trip with filters. Select your departure and arrival times, airlines and total journey duration. You can also sort your results by 'Cheapest,' 'Fastest' or 'Best' flights from Pisa International Airport to Brussels.

Airports in Brussels

Brussels Airport (BRU)

  • Brussels Airport (BRU) to the centre of Brussels takes about 20 minutes by car. The centre is roughly 14 kilometres away.

  • It'll take around 40 minutes when travelling by public transport.

  • The last thing you want is a lengthy journey to your hotel if you're getting in late on a flight from Pisa International Airport to Brussels. Stay at one of these accommodation options near BRU instead:

  • Get your adventure underway by picking up a Brussels Airport rental car. Grab a set of wheels from Keddy By Europcar, Alamo or Europcar and experience the lesser-explored corners of Brussels and beyond.

  • Lock in the best possible rate by reserving your ride from Brussels Airport about three weeks in advance of your flight from PSA to Brussels.

Brussels S. Charleroi Airport (CRL)

  • Brussels S. Charleroi Airport (CRL) is roughly 56 kilometres from the centre of Brussels. Following your flight from Pisa International Airport to Brussels, it'll take you around 55 minutes to get to the heart of the city in a ride-share or cab.

  • Travelling by public transport will take around 1 hour 35 minutes.

  • There are some great places to drop your things at near CRL. Unwind and get cosy after your PSA to Brussels flight at any of these well-located options:

  • Keddy By Europcar, Thrifty and Budget make picking up a Brussels S. Charleroi Airport rental car quick and easy. These trusted companies are located in or around the terminal and will have you behind the wheel before you know it.

  • Avoid last-minute price surges. Reserving your ride two weeks ahead of your arrival at CRL will save you money.

Best time to go to Brussels

  • Carefully consider your dates before booking your flight from Pisa International Airport to Brussels. The city comes alive in peak season, but hotel prices are usually higher and major attractions can get busy. Plan your trip to Brussels in the off-season if you like a more relaxed vibe.

  • The warmest month in Brussels is August, with temperatures ranging between 12ºC and 27ºC. Lock in your Pisa International Airport to Brussels plane ticket then if that's your ideal forecast.

  • January has average temperatures of between -2ºC and 8ºC. Search for a cheap ticket from PSA to Brussels around that time if you like travelling in cooler conditions.

More about Brussels

Explore more of Belgium

  • Ostend is just one of the many cities in Belgium waiting to be discovered once you've seen the sights of Brussels. Around 113 kilometres away to the west, top sights here include Fort Napoleon, The Crystal Ship and Leopoldpark.

  • If there's time to check out another corner of Belgium, consider Verviers, roughly 113 kilometres east of Brussels. Quai Pierre Rapsat, Parc de Séroule and Parc de la Tourelle are among the biggest draws.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.