Cheap Flights from Panama City to Manaus

Compare Panama City to Manaus flight deals

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Flight deals from Panama City to Manaus Airport

Looking for a cheap last-minute deal or the best return flight from Panama City to Manaus Airport? If you want to travel next month, return fares start from $509. Find the lowest prices on one-way and return tickets right here.

Manaus.$400 per passenger.Departing Thu, 2 Apr, returning Mon, 6 Apr.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 2 Apr, arriving in Manaus.Inbound indirect flight with Avianca, departs from Manaus on Mon, 6 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From $400, select.

Manaus.$403 per passenger.Departing Sat, 4 Jul, returning Sat, 18 Jul.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 4 Jul, arriving in Manaus.Inbound indirect flight with Avianca, departs from Manaus on Sat, 18 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $403, select.

Manaus.$403 per passenger.Departing Mon, 26 Oct, returning Mon, 2 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 26 Oct, arriving in Manaus.Inbound indirect flight with Avianca, departs from Manaus on Mon, 2 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $403, select.

Manaus.$488 per passenger.Departing Fri, 27 Mar, returning Mon, 30 Mar.Return flight with Avianca and GOL Linhas Aéreas.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 27 Mar, arriving in Manaus.Inbound indirect flight with GOL Linhas Aéreas, departs from Manaus on Mon, 30 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From $488, select.

Manaus.$506 per passenger.Departing Sun, 25 Oct, returning Mon, 2 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 25 Oct, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Mon, 2 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $506, select.

Manaus.$509 per passenger.Departing Mon, 7 Sep, returning Fri, 11 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 7 Sep, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Fri, 11 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $509, select.

Manaus.$509 per passenger.Departing Fri, 13 Feb, returning Wed, 18 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 13 Feb, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Wed, 18 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $509, select.

Manaus.$635 per passenger.Departing Thu, 2 Apr, returning Mon, 6 Apr.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Thu, 2 Apr, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Mon, 6 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From $635, select.

Manaus.$636 per passenger.Departing Mon, 2 Mar, returning Fri, 6 Mar.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Mon, 2 Mar, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Fri, 6 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From $636, select.

Manaus.$715 per passenger.Departing Fri, 27 Mar, returning Sun, 5 Apr.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 27 Mar, arriving in Manaus.Inbound direct flight with Copa departs from Manaus on Sun, 5 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From $715, select.

Find the cheapest month to fly from Panama City to Manaus

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Manaus flights are currently cheapest in April.

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Direct flights from Panama City to Manaus

Panama City to Manaus: Alternative routes

Compare routes from Panama City to Manaus below. You may find an airport to fly into that's cheaper, faster, or easier than Manaus.

Manaus

11km from central Manaus

ClosestCheapest

from $400

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Panama City to Manaus: Flight information

The things to know before you go.

Cheapest flight found	$400
Cheapest month to fly	April
Average flight time	3 hrs, 54 mins
Most popular airline	Azul Airlines
Average flights per week	59

Finding cheap flights from Panama City to Manaus: Frequently asked questions

How much are return flights from Panama City to Manaus?

The best price we found for a return flight from Panama City to Manaus is $400. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Panama City to Manaus?

3 hours and 54 minutes is the average flight time from Panama City to Manaus.

Which airlines fly direct from Panama City to Manaus?

Azul Airlines, Copa and United fly direct from Panama City to Manaus.

How many flights are there a week from Panama City to Manaus?

As of January 2026, there are 59 flights per week flying from Panama City to Manaus.

When is the cheapest time to fly from Panama City to Manaus?

The cheapest month to fly from Panama City to Manaus is usually April.

Which upcoming date is cheapest to fly from Panama City to Manaus Airport on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Manaus Airport on Thursday, 2 April 2026.

Can I get a direct flight from Panama City to Manaus Airport?

Yes – the average flight time is 3 hours and 54 minutes.

How can I find the best flight deal to Manaus?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Manaus but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Manaus?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Manaus is around 40 days in advance, so don’t leave your flight to the last minute.

Flying from Panama City to Eduardo Gomes International Airport (MAO): What you need to know

Panama City has a couple of airports where you can start your adventure. Check out your options for booking a flight from Panama City to Eduardo Gomes International Airport (MAO) flying out of Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB).
3 hours 55 minutes is the average travel time for a direct Panama City to Eduardo Gomes International Airport flight.
Eduardo Gomes International Airport is located in Manaus. The city is in the UTC-4 timezone and is one hour ahead of Panama City.
Take your pick of 6 direct flights every week between Tocumen International Airport (PTY) and Eduardo Gomes International Airport (MAO). This is the busiest route, with Copa Airlines offering a 9:31pm departure from PTY to MAO.
Leave plenty of time to catch your flight from Panama City to MAO. As a general rule, arrive two hours before international departures and an hour ahead for domestic flights.
Heading away during a peak period like school or public holidays? Expect longer queues at check-in and security. Give yourself extra leeway and arrive up to four hours before international flights and two hours ahead of domestic departures.

Airports in Panama City

Tocumen International Airport (PTY)

You can hop on a direct flight from Panama City to Eduardo Gomes International Airport (MAO) out of Tocumen International Airport (PTY).
You can travel on a direct flight from Panama City to Eduardo Gomes International Airport with Copa Airlines. This top airline offers services from PTY.
Copa Airlines sees the most traveller bookings for flights from PTY to MAO.
With an impressive 86.11% of services arriving as planned, Copa Airlines is the best-performing carrier for punctuality on this route.
You might be able to make your cheap flight from Panama City to MAO even cheaper with a stopover. Just uncheck 'Direct flights only' during your search to find which cities you could pass through. El Dorado International Airport (BOG) is an option when flying out of Tocumen International Airport (PTY).
Located around 21 kilometres from the centre of Panama City, PTY can be reached in about 20 minutes by car, depending on traffic. The journey on public transport will take roughly 1 hour 5 minutes.
Want a stress-free start to your holiday? Stay near Tocumen International Airport. Whether you've booked an early flight from Panama City to Eduardo Gomes International Airport or aren't a fan of being rushed, these hotels offer the perfect solution:
Tocumen International Airport scores high marks for on-time performance. 86.03% of flights that take off from PTY arrive at their destination without delay.

Marcos A. Gelabert International Airport (PAC)

You can reach PAC from central Panama City in about 5 minutes by car, depending on traffic conditions. The ride on public transport will take roughly 25 minutes to cover the 2 kilometres or so.
Want to enjoy an extra night away before boarding your Panama City to MAO flight? Relax in a hotel near Marcos A. Gelabert International Airport before your adventure officially begins. These stays are expecting you:

Panama Pacifico Airport (BLB)

When organising your flight ticket from Panama City to Eduardo Gomes International Airport (MAO) out of Panama Pacifico Airport (BLB), you can choose from a few stopover options. Make a detour to El Dorado International Airport (BOG), one of the busiest transit hubs on this route.
Is around BLB 16 kilometres from central Panama City. The drive from the city centre to the airport takes roughly 20 minutes.
Make catching an early Panama City to Eduardo Gomes International Airport flight the easiest part of your trip. Book a room at one of these accommodation options close to Panama Pacifico Airport and get to your gate feeling relaxed and unhurried:
BLB has an on-time performance rate of 86.75%. This means most of its flights land as expected and your plans go off without a hitch.

About Eduardo Gomes International Airport (MAO)

Have a late flight from Panama City to Eduardo Gomes International Airport? Don't let it leave you bleary-eyed. Check in to one of these hotels near MAO and hit the lights earlier:
Travel at your own pace with an Eduardo Gomes International Airport rental car. Book your wheels from Localiza, Movida or vipservice and see more of Manaus and beyond.
Booking your vehicle around one week ahead of your Panama City to Eduardo Gomes International Airport flight can help you get the lowest rate.

Getting from Eduardo Gomes International Airport (MAO) to central Manaus

Eduardo Gomes International Airport to the centre of Manaus is roughly 48 kilometres. If you're renting a car or taking a cab, do some research to make your trip as easy as possible. Journey times can vary depending on traffic and the time of day.
It typically takes 50 minutes if you're using public transport.

How to find the cheapest flights from Panama City to Eduardo Gomes International Airport (MAO)

The lowest price we've found for a one-way ticket from Panama City to Eduardo Gomes International Airport is $228. For a return flight on this route, the best price is $400. Depending on when you book and the availability, these fares may change.
Get cheap flights from Panama City to MAO by booking two months ahead. Based on our research, that's the ideal time frame for landing a bargain.
Plan your trip for July. That's the best month for scoring an awesome deal on Panama City to Eduardo Gomes International Airport tickets. If you're flexible with your travel dates, use the 'Whole month' tool to find the lowest price across every month.
Finding a cheap flight ticket from Panama City to MAO is a piece of cake with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know as soon as prices go down.
Find a cheap flight from Panama City to Eduardo Gomes International Airport by using the search filters. Choose your ideal times, airlines and number of stops, then sort the results by 'Cheapest' for the best deals.

The best time to fly from Panama City to Eduardo Gomes International Airport (MAO)

April is the quietest month for flights from Panama City to Eduardo Gomes International Airport (MAO), while June is the most popular. Figure out the ideal time to visit Manaus based on whether you want a bustling atmosphere or a more laid-back vibe.
Book a Panama City to MAO flight ticket departing in September if you want to visit the city during its warmest month. Expect temperatures in Manaus to range from 23ºC to 40ºC.
June has temperatures of between 21ºC and 31ºC. Look for cheap tickets from Panama City to Eduardo Gomes International Airport around that time if you like travelling in cooler conditions.

Explore more of Brazil

Itacoatiara is just one of the many cities in Brazil waiting to be explored once you've taken in the sights of Manaus. Around 177 kilometres away to the east, top sights here include Mirante De Itacoatiara, Tunel Verde de Itacoatiara and Adolpho Ducke Forest Reserve.
If you're ready to explore another major stop in Brazil, consider Maues, roughly 257 kilometres east of Manaus. Arte no muro, Cidade Maués-AM and Liceu das Artes - Maués are key reasons to visit.