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Cheap Flights from Panama City to San Diego

Compare Panama City to San Diego flight deals

Find the cheapest month or even day of the year to fly to San Diego

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Flight deals from Panama City to San Diego

Looking for a cheap last-minute deal or the best return flight from Panama City to San Diego? If you want to travel next month, return fares start from $1,263. Find the lowest prices on one-way and return tickets right here.
San Diego.$1,019 per passenger.Departing Fri, 11 Sep, returning Fri, 18 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 11 Sep, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Fri, 18 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,019, select.
San Diego.$1,020 per passenger.Departing Fri, 9 Oct, returning Mon, 12 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 9 Oct, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Mon, 12 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,020, select.
San Diego.$1,064 per passenger.Departing Mon, 24 Aug, returning Sat, 29 Aug.Return flight with United.Outbound indirect flight with United, departs from Panama City Tocumen International on Mon, 24 Aug, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Sat, 29 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,064, select.
San Diego.$1,210 per passenger.Departing Sun, 30 Aug, returning Fri, 4 Sep.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 30 Aug, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Fri, 4 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,210, select.
San Diego.$1,212 per passenger.Departing Sun, 16 Aug, returning Sun, 23 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 16 Aug, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Sun, 23 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,212, select.
San Diego.$1,214 per passenger.Departing Thu, 30 Jul, returning Mon, 24 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Thu, 30 Jul, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Mon, 24 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,214, select.
San Diego.$1,263 per passenger.Departing Wed, 15 Jul, returning Wed, 29 Jul.Return flight with United.Outbound indirect flight with United, departs from Panama City Tocumen International on Wed, 15 Jul, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Wed, 29 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,263, select.
San Diego.$1,327 per passenger.Departing Wed, 8 Jul, returning Mon, 13 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 8 Jul, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Mon, 13 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,327, select.
San Diego.$1,351 per passenger.Departing Sun, 28 Jun, returning Sun, 5 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 28 Jun, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Sun, 5 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,351, select.
San Diego.$1,373 per passenger.Departing Sun, 2 Aug, returning Mon, 2 Nov.Return flight with United.Outbound indirect flight with United, departs from Panama City Tocumen International on Sun, 2 Aug, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Mon, 2 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,373, select.
San Diego.$1,388 per passenger.Departing Sat, 26 Dec, returning Sat, 9 Jan.Return flight with United.Outbound indirect flight with United, departs from Panama City Tocumen International on Sat, 26 Dec, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Sat, 9 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,388, select.
San Diego.$1,437 per passenger.Departing Wed, 17 Jun, returning Tue, 18 Aug.Return flight with United.Outbound indirect flight with United, departs from Panama City Tocumen International on Wed, 17 Jun, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Tue, 18 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,437, select.
San Diego.$1,453 per passenger.Departing Fri, 19 Jun, returning Fri, 26 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Fri, 19 Jun, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Fri, 26 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,453, select.
San Diego.$1,512 per passenger.Departing Sun, 2 Aug, returning Mon, 2 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 2 Aug, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Mon, 2 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,512, select.
San Diego.$1,515 per passenger.Departing Wed, 3 Feb, returning Wed, 10 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 3 Feb, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Wed, 10 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,515, select.
San Diego.$1,609 per passenger.Departing Sat, 26 Dec, returning Sat, 9 Jan.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sat, 26 Dec, arriving in San Diego International.Inbound direct flight with Copa departs from San Diego International on Sat, 9 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From $1,609, select.

Find the cheapest month to fly from Panama City to San Diego

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to San Diego flights are currently cheapest in September.
Jun
from $1,453
Jul
from $1,263
Aug
from $1,064
Sep
from $1,019
Oct
from $1,020
Nov
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Dec
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Jan
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Feb
from $1,515
Mar
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Apr
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May
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Direct flights from Panama City to San Diego

Alternative Panama City to San Diego routes

Looking for the cheapest, fastest or easiest route from Panama City to San Diego? You could fly into the following airports instead.

San Diego International

4km from central San Diego
ClosestCheapest
from $1,019
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McClellan-Palomar

48km from central San Diego
Search flights

Panama City to San Diego: Flight information

The things to know before you go.
Cheapest flight found$1,019
Cheapest month to flySeptember
Average flight time6 hrs, 40 mins
Most popular airlineCopa
Average flights per week11

Finding cheap flights from Panama City to San Diego: Frequently asked questions

There are 2 airports in San Diego: San Diego International and McClellan-Palomar.
The best price we found for a return flight from Panama City to San Diego is $1,019. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 40 minutes is the average flight time from Panama City to San Diego.
Copa and United fly direct from Panama City to San Diego.
As of June 2026, there are 11 flights per week flying from Panama City to San Diego.
The cheapest month to fly from Panama City to San Diego is usually September.
If you're flying from Panama City, the cheapest airport near San Diego is San Diego International – which is 4.1 km away from the centre of San Diego. We've found flights into this airport from $1,019.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to San Diego on Friday, 11 September 2026.
Yes – the average flight time is 6 hours and 40 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to San Diego but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to San Diego is around 40 days in advance, so don’t leave your flight to the last minute.
In June, the average temperature is usually around 19°C. August is typically the warmest month in San Diego, when it usually averages around 28°C. You can expect the least rain in June. The coldest month is December, with temperatures averaging 10°C. The rainiest month is February.
The cheapest airline that flies to San Diego is Copa .

Travelling from Panama City to San Diego: what you need to know

  • There are a couple of main airports to choose from in Panama City. Check out your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when reserving your flight from Panama City to San Diego.

  • San Diego International Airport (SAN) is the primary arrival point in San Diego.

  • Around 6 hours 40 minutes is how long you can expect to be travelling on a direct Panama City to San Diego flight.

  • The timezone in San Diego is UTC-7, which is two hours behind Panama City.

  • The most popular route for flights from Panama City to San Diego is from Tocumen International Airport (PTY) to San Diego International Airport (SAN). You can choose from three weekly services between these two airports. If you want to maximise your time on arrival, the earliest flight from PTY to SAN is the 13:15 Copa Airlines service. If you have other commitments or plans on your day of travel, the last departure is at 13:15 with Copa Airlines.

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to board your Panama City to San Diego flight.

  • Be prepared for longer lines in popular months like June. Arriving up to four hours in advance for an international flight and two hours for a domestic departure is a smart move.

How to find the cheapest flights from Panama City to San Diego

  • Book 11 months before your departure date. Pricing trends show that this is the ideal window for finding cheap Panama City to San Diego flights.

  • February is the best month for picking up an amazing deal on a plane ticket from Panama City to San Diego. If you'd like to travel during a different time of year, the 'Whole month' tool will give you the lowest prices for every month.

  • Getting a cheap flight from Panama City to San Diego couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch when a better deal is available.

  • Choose your ideal arrival and departure times, airlines and number of stops by using the filters. Alternatively, sort your Panama City to San Diego flight results by 'Best,' 'Fastest' or 'Cheapest.'

Flying from Panama City

Tocumen International Airport (PTY)

  • If you're after a direct flight from Panama City to San Diego, you can leave from Tocumen International Airport (PTY). Get from PTY to San Diego International Airport (SAN) in one continuous trip.

  • Copa Airlines is a well-known airline that offers direct Panama City to San Diego plane tickets from PTY.

  • Stopovers are the perfect opportunity to break up your trip — and perhaps even tour another city. When browsing Panama City to San Diego flights leaving from Tocumen International Airport, uncheck the 'Direct flights only' box to see where you can visit along the way. Popular options include:

    • Denver International Airport (DEN)

    • George Bush Intercontinental Airport (IAH)

    • Austin-Bergstrom International Airport (AUS)

  • PTY is about 18 kilometres from central Panama City. If you're catching a cab, driving or ride-sharing from the centre, it'll take 20 minutes or so to get there, depending on the traffic. If you're planning to take public transport, expect the trip time to be around 1 hour 5 minutes.

  • Searching for a convenient hotel close to Tocumen International Airport? If you're catching an early flight from Panama City to San Diego, these stays will have you sleeping moments from your departure gate:

  • Tocumen International Airport earns top marks for on-time performance. 86.03% of flights that take off from PTY land on time.

Panama Pacifico Airport (BLB)

  • Driving from central Panama City to BLB typically takes 20 minutes, depending on traffic. It's around 11 kilometres from the city centre to the airport.

  • Want to treat yourself to an extra night away before your flight from Panama City to San Diego? Relax in a hotel near Panama Pacifico Airport before your trip officially begins. These stays are calling your name:

  • The majority of flights that leave Panama Pacifico Airport land at their destination right on cue. It maintains a strong on-time performance rate of 87%.

Arriving in San Diego

San Diego International Airport (SAN)

  • The distance from San Diego International Airport (SAN) to central San Diego is roughly 5 kilometres. It takes about 10 minutes to reach the centre driving.

  • It typically takes 20 minutes to get there when travelling by public transport.

  • The last thing you need is a long journey to your hotel if you're arriving on a late flight from Panama City to San Diego. Check in to one of these accommodation options near SAN instead:

  • Travel at your own speed with a San Diego International Airport rental car. Pick up your wheels from Thrifty, Dollar or Budget and find adventure across San Diego and beyond.

  • Lock in the best deal by booking your ride from San Diego International Airport around two weeks in advance of your trip.

  • You'll find SAN at N Harbour Dr.

McClellan-Palomar Airport (CLD)

  • McClellan-Palomar Airport (CLD) is about 48 kilometres from the centre of San Diego. Once you've disembarked your flight from Panama City to San Diego, it'll take you approximately 40 minutes to reach the heart of the city in a ride-share or cab.

  • If you choose to travel on public transport, you'll get to the city centre in 2 hours 15 minutes or so.

  • The quickest way to reach your destination is with a McClellan-Palomar Airport rental car. Pick up your wheels from Budget, Hertz or Avis and get going in the blink of an eye.

  • Avoid the long lines and paperwork at the rental desk by having everything prearranged. Reserve your ride from CLD ahead of time so you can just grab the keys and be on your way.

Best time to go to San Diego

  • It's time to plan your travel dates for your flight from Panama City to San Diego. July is the most popular month to visit San Diego. If you want a more peaceful vibe, go in May.

  • The warmest month in San Diego is August, with temperatures ranging between 17ºC and 28ºC. Book your Panama City to San Diego ticket then if that's your idea of comfortable weather.

  • If you like cooler conditions, look for a cheap flight from Panama City to San Diego in February when temperatures average between 7ºC and 23ºC.

More about San Diego

  • When it comes to looking for somewhere to rest your head, you'll find the best places to stay in San Diego right here. Browse these hotels as soon as you've booked your flight from Panama City to San Diego:

  • San Diego Zoo and USS Midway Museum are just two of the leading attractions to put on your San Diego to-do list. Keep the sightseeing going at SeaWorld San Diego.

Explore more of United States

  • You've done San Diego, now it's time to discover other parts of United States. Journey around 177 kilometres north-west to Los Angeles to check off its top attractions. From Griffith Observatory to The Broad and La Brea Tar Pits & Museum, you've got a jam-packed schedule ahead.

  • Phoenix is another must-experience destination in United States and is around 483 kilometres east of San Diego. No journey is complete without visiting Desert Botanical Garden, Heard Museum and Papago Park.

More travel options

Plan the rest of your trip from Panama City to San Diego

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.