Cheap Flights from Santo Domingo to Sao Paulo

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Flight deals from Santo Domingo to Sao Paulo

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Sao Paulo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santo Domingo to Sao Paulo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Sao Paulo flights are currently cheapest in April.

Alternative Santo Domingo to Sao Paulo routes

Looking for the cheapest, fastest or easiest route from Santo Domingo to Sao Paulo? You could fly into the following airports instead.

Santo Domingo to Sao Paulo: Flight information

The things to know before you go.
Cheapest flight found$788
Cheapest month to flyApril

Finding cheap flights from Santo Domingo to Sao Paulo: Frequently asked questions

There are 4 airports in Sao Paulo: Sao Paulo Congonhas, Sao Paulo Guarulhos, Sao Paulo Viracopos, and Sao Jose Dos Campos.
The best price we found for a return flight from Santo Domingo to Sao Paulo is $786. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santo Domingo to Sao Paulo. But we found flights with one or more stops from $786.
As of December 2025, there are no flights flying from Santo Domingo to Sao Paulo.
The cheapest month to fly from Santo Domingo to Sao Paulo is usually April.
If you're flying from Santo Domingo, the cheapest airport near Sao Paulo is Sao Paulo Guarulhos – which is 20.4 km away from the centre of Sao Paulo. We've found flights into this airport from $786.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Sao Paulo on Friday, 10 April 2026.
No airlines currently offer direct flights between Santo Domingo and Sao Paulo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 23°C. February is typically the warmest month in Sao Paulo, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is July, with temperatures averaging 12°C. The rainiest month is January.
The cheapest airline that flies to Sao Paulo is Arajet .

Travelling from Santo Domingo to Sao Paulo: what you need to know

  • There are two main airports you can fly out of in Santo Domingo. Check out your options leaving from Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ) when searching for a flight from Santo Domingo to Sao Paulo.

  • Hop off your plane in Sao Paulo at Sao Paulo-Guarulhos International Airport (GRU) or Viracopos Airport (VCP).

  • Sao Paulo's timezone is UTC-3, which makes Sao Paulo one hour ahead of Santo Domingo.

  • Give yourself enough time to get on your Santo Domingo to Sao Paulo flight. As a general rule, arrive at least two hours before international departures and an hour ahead for domestic flights.

  • Be prepared for longer lines in popular months like August. Arriving up to four hours ahead of international flights and two hours for a domestic departure will give you plenty of time for security and boarding.

How to find the cheapest flights from Santo Domingo to Sao Paulo

  • Don't leave everything to the last moment. You're more likely to find cheap Santo Domingo to Sao Paulo flights if you book in advance. Airlines often have some excellent early bird discounts.

  • If you're willing to be flexible with your trip dates, use the 'Whole month' tool. It'll show you the cheapest price in every month when searching for your plane ticket from Santo Domingo to Sao Paulo.

  • Getting a cheap flight from Santo Domingo to Sao Paulo couldn't be easier with Price Alerts. Simply set up one of these automatic alerts and we'll let you know when there's a better deal.

  • Pick your ideal arrival and departure times, number of stops and airlines by using the filters. Alternatively, sort your Santo Domingo to Sao Paulo flight results by 'Fastest,' 'Cheapest' or 'Best.'

Flying from Santo Domingo

Las Americas International Airport (SDQ)

  • We make it easy to book a Santo Domingo to Sao Paulo flight with a stopover. To see all your options departing from Las Americas International Airport, deselect 'Direct flights only.' Next, select a flight with a stop long enough to tour the city of your choice. Some popular stopovers include:

    • Miami International Airport (MIA)

    • El Dorado International Airport (BOG)

    • Tocumen International Airport (PTY)

  • To get to SDQ from central Santo Domingo, it takes about 30 minutes if you're going by car. It's roughly 27 kilometres from the airport to the city centre.

  • Have an early flight from Santo Domingo to Sao Paulo? Avoid the stress of rushing to the airport (and get some extra shut-eye) by choosing one of these stays close to Las Americas International Airport:

  • 72.45% of flights leaving from Las Americas International Airport arrive at their destination on time.

Arriving in Sao Paulo

Sao Paulo-Guarulhos International Airport (GRU)

  • The distance from Sao Paulo-Guarulhos International Airport (GRU) to central Sao Paulo is roughly 21 kilometres. It takes around 30 minutes to reach the centre driving.

  • If you're using public transport, expect a journey time of around 1 hour 20 minutes.

  • Consider staying in a hotel near GRU if you have a late flight from Santo Domingo to Sao Paulo. Check in to one of these accommodation options and avoid the hassle of a long transfer:

  • Begin your adventure by picking up a Sao Paulo-Guarulhos International Airport rental car. Grab your wheels from Foco, Localiza or Movida to explore Sao Paulo and beyond.

  • Secure the lowest price by reserving your ride from Sao Paulo-Guarulhos International Airport around two weeks before your trip.

Sao Paulo/Congonhas Airport (CGH)

  • As soon as your flight from Santo Domingo to Sao Paulo has arrived, you can reach the city centre in about 15 minutes by car. Central Sao Paulo is roughly 8 kilometres from Sao Paulo/Congonhas Airport (CGH).

  • If you hop on public transport, you'll get to the city centre in 35 minutes or so.

  • After your flight from Santo Domingo to Sao Paulo, tuck yourself in at a hotel near VCP. These are some great options that'll help you get into relaxation mode:

  • The fastest way to reach your destination is with a Sao Paulo/Congonhas Airport rental car. Grab a set of wheels from Foco, Localiza or Movida and hit the road in a heartbeat.

  • Avoid last-minute price surges. Reserving your ride three weeks before your arrival at CGH will save you money.

Viracopos Airport (VCP)

  • Hop off your flight from Santo Domingo to Sao Paulo and head directly to your hotel or start sightseeing right away. Central Sao Paulo is around 80 kilometres from Viracopos Airport (VCP) and takes roughly 1 hour 15 minutes to reach driving.

  • If you're using public transport, the journey will take you about 3 hours 25 minutes.

  • Stay in control of the next leg of your journey by picking up a Viracopos Airport rental car. Foco, Localiza and Movida will get you on the road.

  • Plan ahead and get the perks. Book your ride from VCP four weeks before your flight from Santo Domingo to Sao Paulo for the best rates.

Best time to go to Sao Paulo

  • July is the most popular month for flights from Santo Domingo to Sao Paulo. To steer clear of the crowds, visit Sao Paulo in April.

  • The warmest month in Sao Paulo is February, with temperatures ranging between 18ºC and 28ºC. Lock in your Santo Domingo to Sao Paulo ticket then if you enjoy this type of weather.

  • If you like travelling in cooler conditions, search for a cheap flight from Santo Domingo to Sao Paulo in July when temperatures average between 12ºC and 25ºC.

More about Sao Paulo

  • When it comes to looking for somewhere to lay your head, you'll find the best places to stay in Sao Paulo right here. Explore these hotels once you've booked your flight from Santo Domingo to Sao Paulo:

  • There are so many things to see and do in this city it can be difficult to know where to start. Sao Paulo Museum of Art, Ibirapuera Park and Avenida Paulista are top attractions which should be on any good Sao Paulo itinerary.

Explore more of Brazil

  • Belo Horizonte is just one of the many places in Brazil waiting to be explored once you've seen Sao Paulo. Around 499 kilometres to the north-east, popular attractions include Abilio Barreto Historical Museum, Matiz Arte Objeto and Deck Vertedouro.

  • Curitiba is another must-experience destination in Brazil and is around 338 kilometres south-west of Sao Paulo. No journey is complete without a visit to Jardim Botanico de Curitiba, Museu Oscar Niemeyer and Largo da Ordem.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.