Cheap Flights from San Francisco International to Santiago

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      Compare San Francisco International to Santiago flight deals

      Find the cheapest month or even day of the year to fly to Santiago

      Book the best Santiago fare with no extra fees

      Flight deals from San Francisco International to Santiago

      Looking for a cheap last-minute deal or the best return flight from San Francisco International Airport to Santiago Airport? If you want to travel next month, return fares start from $1,540. Find the lowest prices on one-way and return tickets right here.
      How did we find these deals? The deals you see here are the lowest prices for flight tickets from San Francisco International to Santiago found in the last 4 days, and are subject to change and availability.

      Find the cheapest month to fly from San Francisco International to Santiago

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Santiago flights are currently cheapest in June.

      San Francisco International to Santiago: Alternative routes

      Compare routes from San Francisco International to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

      San Francisco to Santiago: Flight information

      The things to know before you go.
      Cheapest flight found$1,346
      Cheapest month to flyOctober

      Finding cheap flights from San Francisco International to Santiago: Frequently asked questions

      The best price we found for a return flight from San Francisco International to Santiago is $1,346. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from San Francisco International to Santiago. But we found flights with one or more stops from $1,346.
      As of September 2026, there are no flights flying from San Francisco International to Santiago.
      The cheapest month to fly from San Francisco International to Santiago is usually October.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Santiago Airport on Wednesday, 28 October 2026.
      No airlines currently offer direct flights between San Francisco International Airport and Santiago Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, United offers the cheapest flight tickets to Santiago.

      Flying from San Francisco International Airport (SFO) to Santiago Airport (STI): what you need to know

      • The timezone in Santiago is UTC-4, which is four hours ahead of San Francisco.

      • Arrive at the airport on time so you don't miss your SFO to STI flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid any last-minute rush.

      • You can expect longer queues during popular months such as July. Arriving up to four hours ahead of international flights and two hours for domestic departures will help ensure a smooth travel experience.

      • We make it a breeze to book a flight with a stopover. To see all your options for tickets from San Francisco International Airport to Santiago Airport, uncheck 'Direct flights only.' Then, pick a flight with a stop long enough to explore your chosen city. Top stopovers between SFO and STI include:

        • New York John F. Kennedy Airport

        • New York Newark Airport

        • Miami International Airport

      How to find the cheapest flights from San Francisco International Airport (SFO) to Santiago Airport (STI)

      • The lowest price we've found for a one-way San Francisco International Airport to Santiago Airport flight is $718. A return plane ticket right now is $1,346. Depending on the availability and when you book, these fares can change.

      • Don't leave everything to the last minute. You're more likely to find cheap tickets from SFO to STI if you book in advance. Airlines often offer some excellent early bird rates.

      • If you're flexible with your travel dates, use the 'Whole month' search tool. It'll show you the cheapest price in each month when looking for a flight from San Francisco International Airport to Santiago Airport.

      • Never miss a deal on cheap flights from SFO to STI by setting up a Price Alert. You'll receive an email or notification through the app when a new low fare is offered.

      • Choose your preferred departure and arrival times, number of stops and airlines with the filters. Alternatively, sort your results by 'Cheapest' to see the best deals on flights from San Francisco International Airport to Santiago Airport.

      Handy information about San Francisco International Airport (SFO)

      • Of the departures from San Francisco International Airport, 78% touch down on time at their destination.

      • Central San Francisco to San Francisco International Airport is around 21 kilometres. Depending on traffic, it'll take about 25 minutes to get there if you're catching a taxi, ride-sharing or driving.

      • The trip when using public transport takes roughly 35 minutes.

      • Looking for a convenient hotel close to SFO? If you're boarding an early flight from San Francisco International Airport to Santiago Airport, these stays will have you moments from your departure lounge:

      Arriving at Santiago Airport (STI)

      • The last thing you want is a long trip to your hotel if you're arriving on a late San Francisco International Airport to Santiago Airport flight. Check in to one of these accommodation options near STI instead:

      • Grab a Santiago Airport rental car and discover Santiago and beyond with your own wheels. America, Zezgo Rent a Car and Alamo are top providers to choose from here.

      • Lock in the best possible rate by booking your ride from Santiago Airport about one week before your departure date.

      Getting from Santiago Airport (STI) to central Santiago

      • From Santiago Airport, Santiago is approximately 16 kilometres away. It takes around 25 minutes to reach the centre driving.

      • It takes around 40 minutes when travelling by public transport.

      When to fly to Santiago Airport (STI)

      • August is the busiest month for flights from San Francisco International Airport to Santiago Airport. To avoid the crowds, travel to Santiago in October.

      • When reserving your flight from San Francisco International Airport to Santiago Airport, consider the kind of weather you enjoy. August is the warmest month in Santiago, with temperatures ranging from 21ºC to 33ºC.

      • Search for cheap tickets from SFO to STI in January if you'd rather travel during cooler conditions. Temperatures are at their lowest around then, ranging between 16ºC and 29ºC on average.

      Explore more of the Dominican Republic

      • Santiago has plenty going for it, but there are so many other parts of the Dominican Republic just waiting to be discovered. Around 137 kilometres south-east of Santiago, a visit to Santo Domingo will fill your itinerary to the brim. Don't miss top attractions like Catedral Primada de las Americas, Alcazar de Colon and The Cathedral of the Americas.

      • Around 145 kilometres south-east of Santiago, Santo Domingo Este is another essential stop in the Dominican Republic. Experience the best of this destination with a visit to Lago los tres ojos, National Aquarium and La Cueva del Eden.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.