Cheap Flights from Madison to Knoxville from $541

Compare Madison to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Madison to Knoxville

Looking for a cheap last-minute deal or the best return flight from Madison Airport to Knoxville Airport? If you want to travel next month, return fares start from $578. Find the lowest prices on one-way and return tickets right here.

Knoxville.$541 per passenger.Departing Sat, 11 Jul, returning Thu, 16 Jul.Return flight with United.Outbound indirect flight with United, departs from Madison on Sat, 11 Jul, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Thu, 16 Jul, arriving in Madison.Price includes taxes and charges.From $541, select.

Knoxville.$565 per passenger.Departing Sat, 15 Aug, returning Thu, 20 Aug.Return flight with United.Outbound indirect flight with United, departs from Madison on Sat, 15 Aug, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Thu, 20 Aug, arriving in Madison.Price includes taxes and charges.From $565, select.

Knoxville.$573 per passenger.Departing Tue, 28 Apr, returning Sat, 2 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Madison on Tue, 28 Apr, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sat, 2 May, arriving in Madison.Price includes taxes and charges.From $573, select.

Knoxville.$578 per passenger.Departing Wed, 6 May, returning Thu, 7 May.Return flight with United.Outbound indirect flight with United, departs from Madison on Wed, 6 May, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Thu, 7 May, arriving in Madison.Price includes taxes and charges.From $578, select.

Knoxville.$579 per passenger.Departing Sat, 25 Apr, returning Wed, 29 Apr.Return flight with United.Outbound indirect flight with United, departs from Madison on Sat, 25 Apr, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Wed, 29 Apr, arriving in Madison.Price includes taxes and charges.From $579, select.

Knoxville.$581 per passenger.Departing Wed, 22 Jul, returning Sat, 1 Aug.Return flight with United.Outbound indirect flight with United, departs from Madison on Wed, 22 Jul, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Sat, 1 Aug, arriving in Madison.Price includes taxes and charges.From $581, select.

Knoxville.$886 per passenger.Departing Wed, 17 Jun, returning Sun, 21 Jun.Return flight with United.Outbound indirect flight with United, departs from Madison on Wed, 17 Jun, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Sun, 21 Jun, arriving in Madison.Price includes taxes and charges.From $886, select.

Knoxville.$1,010 per passenger.Departing Fri, 25 Sep, returning Mon, 28 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Madison on Fri, 25 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 28 Sep, arriving in Madison.Price includes taxes and charges.From $1,010, select.

Knoxville.$1,183 per passenger.Departing Fri, 9 Oct, returning Sun, 11 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Madison on Fri, 9 Oct, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sun, 11 Oct, arriving in Madison.Price includes taxes and charges.From $1,183, select.

Find the cheapest month to fly from Madison to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madison to Knoxville flights are currently cheapest in July.

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Madison to Knoxville: Alternative routes

Compare routes from Madison to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville

ClosestCheapest

from $541

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Madison to Knoxville: Flight information

The things to know before you go.

Cheapest flight found	$541
Cheapest month to fly	July

Finding cheap flights from Madison to Knoxville: Frequently asked questions

How much are return flights from Madison to Knoxville?

The best price we found for a return flight from Madison to Knoxville is $541. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Madison to Knoxville?

Currently, there are no airlines that fly direct from Madison to Knoxville. But we found flights with one or more stops from $541.

How many flights are there a week from Madison to Knoxville?

As of April 2026, there are no flights flying from Madison to Knoxville.

When is the cheapest time to fly from Madison to Knoxville?

The cheapest month to fly from Madison to Knoxville is usually July.

Which upcoming date is cheapest to fly from Madison Airport to Knoxville Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madison Airport to Knoxville Airport on Saturday, 11 July 2026.

Can I get a direct flight from Madison Airport to Knoxville Airport?

No airlines currently offer direct flights between Madison Airport and Knoxville Airport. Most routes have one or more stops.

How can I find the best flight deal to Knoxville?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Knoxville?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Madison Airport to Knoxville with?

Currently, United offers the cheapest flight tickets to Knoxville.

Travelling from Dane County Regional Airport (MSN) to McGhee Tyson Airport (TYS): what you need to know

Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for hassle-free flying. Make sure you're at the airport on time to board your MSN to TYS flight.
You can expect longer lines in popular months such as August. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a good idea.
If you want to include a stop along the way, simply deselect 'Direct flights only' when searching for your ticket from Dane County Regional Airport to McGhee Tyson Airport. These are the most popular stopovers between MSN and TYS:
- O'Hare International Airport
- Minneapolis-St. Paul International Airport
- Charlotte Douglas International Airport

How to find the cheapest flights from Dane County Regional Airport (MSN) to McGhee Tyson Airport (TYS)

The lowest price we've found for a one-way Dane County Regional Airport to McGhee Tyson Airport flight is $199. A round-trip fare right now is $541. Depending on the availability and when you book, these fares could change.
Don't leave everything to the last minute. You're more likely to get cheap tickets from MSN to TYS if you book ahead. Airlines often offer some excellent early bird discounts.
The 'Whole month' tool shows you the cheapest flights from Dane County Regional Airport to McGhee Tyson Airport across the month. It's a great way to find a bargain if your travel plans are flexible.
Getting your hands on cheap flights from MSN to TYS is easy with Price Alerts. All you need to do is set up one of these automatic alerts and we'll let you know when a lower fare pops up.
Discover the perfect flight for you by using the filters. To see the 'Best,' 'Fastest' or 'Cheapest' flights from Dane County Regional Airport to McGhee Tyson Airport, use the 'Sort by' function. You can also filter by arrival and departure times, airline, and number of stops.

Handy information about Dane County Regional Airport (MSN)

The address for MSN is 4000 International Lane.
Of all flights departing from Dane County Regional Airport, 77.89% arrive as scheduled at their destination.
Dane County Regional Airport is about 14 kilometres from central Madison. If you're driving, ride-sharing or catching a cab from the centre, it'll take you 20 minutes or so to get there, depending on the traffic.
You can expect a trip time of about 1 hour 10 minutes when using public transport.
Booked an early flight from Dane County Regional Airport to McGhee Tyson Airport? Avoid the stress of rushing to the terminal (and catch some extra z's) by picking one of these hotels near MSN:

Arriving at McGhee Tyson Airport (TYS)

Book a hotel near TYS if you're catching a late Dane County Regional Airport to McGhee Tyson Airport flight. Choose one of these options and make your arrival easier:
Travel at your own pace with a McGhee Tyson Airport rental car. Pick up a set of wheels from Budget, Alamo or Avis and venture far and wide through Knoxville and beyond.
To get the lowest price, reserve your ride from McGhee Tyson Airport about three weeks in advance.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

You'll find TYS at 2055 Alcoa Highway.
McGhee Tyson Airport to central Knoxville has a drive time of about 20 minutes. It's approximately 23 kilometres away.

When to fly to McGhee Tyson Airport (TYS)

It's time to choose your travel dates for your flight from Dane County Regional Airport to McGhee Tyson Airport. July is the most popular month to head to Knoxville. If you want a more relaxed vibe, go in February.
Lock in your flight from Dane County Regional Airport to McGhee Tyson Airport for July if you'd like to explore Knoxville during its warmest month. You can expect temperatures of between 17ºC and 32ºC.
January sees average temperatures of between -6ºC and 11ºC. Search for cheap tickets from MSN to TYS around that time if you want to travel when it's cooler.

Explore more of United States

Knoxville has loads to offer, but there are so many other corners of United States waiting to be explored. About 451 kilometres north of Knoxville, a trip to Columbus will keep your itinerary busy. Don't miss top attractions like Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.
Around 467 kilometres north-west of Knoxville, Indianapolis is another favourite stop in United States. Get a taste of what this destination has to offer at The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.