Flights from San Francisco to Santiago Metropolitan Region

Flight deals from San Francisco to Santiago Metropolitan Region

Looking for a cheap last-minute deal or the best return flight from San Francisco to Santiago Metropolitan Region? If you want to travel next month, return fares start from $1,216. Find the lowest prices on one-way and return tickets right here.

Flying from San Francisco to Santiago Metropolitan Region

Arm yourself with these facts on the fly.
Cheapest flight found$1,140
Cheapest month to flyAugust
Cheapest airport to fly fromSan Francisco International

Frequently asked questions

We looked at all of the upcoming return flights from San Francisco to Santiago Metropolitan Region we could find over the next 12 months. It looks like $1,147 is the best price. This is good, compared to the average Santiago Metropolitan Region ticket price of $1,147.
The cheapest month to fly from San Francisco to Santiago Metropolitan Region is currently August.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from San Francisco to Santiago Metropolitan Region on Wednesday, 26 August 2026.
Currently, there aren't any direct flights from San Francisco to Santiago Metropolitan Region, but you can still fly with a stopover.
If you're flying from San Francisco, the cheapest city in Santiago Metropolitan Region to fly into is Santiago. The cheapest airport serving Santiago at the moment is Santiago Arturo Merino Benitez.